1. Stem Cell/Wnt
  2. Oct3/4
  3. Oct4 inducer-1

Oct4 inducer-1 (compound OAC-3) 是一种有效的 Oct4 激活剂。Oct4 inducer-1 激活 Oct4 和 Nanog 启动子,促进诱导多能干细胞 (iPSC) 的形成。Oct4 inducer-1 通过提高效率和缩短重编程时间,促进了细胞的重编程。

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Oct4 inducer-1 Chemical Structure

Oct4 inducer-1 Chemical Structure

CAS No. : 182564-41-6

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5 mg ¥930
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10 mg ¥1580
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25 mg ¥3150
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50 mg ¥5050
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100 mg ¥7800
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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oct4 inducer-1 (compound OAC-3) is a potent Oct4 activator. Oct4 inducer-1 activates Oct4 and Nanog promoters and enhances induced pluripotent stem cells (iPSC) formation. Oct4 inducer-1 facilitates the reprogramming of cells by enhancing efficiency and shortening the reprogramming time[1].

体外研究
(In Vitro)

Oct4 inducer-1 (compound OAC-3; 1 μM) enhances reprogramming efficiency by activating Oct4-luc reporter and Nanog-luc reporter in embryonic stem cells (ESCs). Oct4 inducer-1 increases induced pluripotent stem cells (iPSC) generation and accelerates the appearance of iPSC-like colonies[1].
Oct4 inducer-1 (1 μM; 4F (OSKM) infected mouse embryonic fibroblast (MEF)) enhances reprogramming efficiency in iSF1 media[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

254.26

Formula

C15H11FN2O

CAS 号
性状

固体

颜色

Light brown to brown

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 250 mg/mL (983.25 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.9330 mL 19.6649 mL 39.3298 mL
5 mM 0.7866 mL 3.9330 mL 7.8660 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Oct4 inducer-1 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9330 mL 19.6649 mL 39.3298 mL 98.3246 mL
5 mM 0.7866 mL 3.9330 mL 7.8660 mL 19.6649 mL
10 mM 0.3933 mL 1.9665 mL 3.9330 mL 9.8325 mL
15 mM 0.2622 mL 1.3110 mL 2.6220 mL 6.5550 mL
20 mM 0.1966 mL 0.9832 mL 1.9665 mL 4.9162 mL
25 mM 0.1573 mL 0.7866 mL 1.5732 mL 3.9330 mL
30 mM 0.1311 mL 0.6555 mL 1.3110 mL 3.2775 mL
40 mM 0.0983 mL 0.4916 mL 0.9832 mL 2.4581 mL
50 mM 0.0787 mL 0.3933 mL 0.7866 mL 1.9665 mL
60 mM 0.0655 mL 0.3277 mL 0.6555 mL 1.6387 mL
80 mM 0.0492 mL 0.2458 mL 0.4916 mL 1.2291 mL
100 mM 0.0393 mL 0.1966 mL 0.3933 mL 0.9832 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Oct4 inducer-1
目录号:
HY-119672
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