1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Hepcidin

Hepcidin (铁调素)

Hepcidin is a 25-amino-acid peptide hormone secreted by hepatocytes. Hepcidin determines plasma iron concentrations and total body iron content. The function of hepcidin is to control the activity of the cellular iron exporter ferroportin, which delivers iron to plasma from intestinal iron absorption and from iron stores.

Hepcidin 相关产品 (1):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-113066
    Guanosine 5'-diphosphate

    鸟苷-5’-二磷酸

    Inhibitor
    Guanosine 5'-diphosphate (GDP) 是一种核苷二磷酸,可激活 5'-三磷酸腺苷敏感的 K+ 通道。Guanosine 5'-diphosphate 是一种潜在的铁动员剂,可阻断铁调素-铁转运蛋白 (hepcidin-ferroportin) 相互作用并调节 IL-6/stat-3 通路。Guanosine 5'-diphosphate 可用于炎症研究,如炎症性贫血 (AI)。
    Guanosine 5'-diphosphate