Synaptic Vesicle Proteins (突触囊泡蛋白)

Synaptic vesicle protein is the important component of synaptic vesicle, that plays a role in the storage and transportation of neurotransmitters, vesicle fusion and release, as well as vesicle recycling/reusing. Synaptic vesicle protein includes synaptophysin, synaptotagmin, vesicle associated membrane protein (VAMP), synaptogyrin, vesicular neurotransmitter transporters, which could be divided into two classes: transport proteins involved in neurotransmitter uptake and trafficking proteins that participate in synaptic vesicle exo- and endocytosis and recycling. Synaptic vesicle protein cause the neurological diseases, such as Alzheimer's disease, epilepsy, depression^[1][2].