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Seletracetam (Synonyms: Ucb 44212)

目录号: HY-119810
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Seletracetam (Ucb 44212) 是一种类似于抗癫痫药 Levetiracetam 的类似物。Seletracetam 是一种用于癫痫研究的小分子 SV2A 调制剂。

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Seletracetam Chemical Structure

Seletracetam Chemical Structure

CAS No. : 357336-74-4

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Description

Seletracetam (Ucb 44212) is an analog of the antiepileptic agent Levetiracetam. Seletracetam is a small molecule SV2A modulator for the research of epilepsy[1][2][3].

IC50 & Target

SV2A[1]

In Vitro

Seletracetam decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle protein SV2A[2].
Seletracetam decreases synaptic responses in a time-, frequency- and concentration-dependent manner[2].
Seletracetam modifies rates of presynaptic release[2].
Seletracetam inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro[2].

Molecular Weight

232.23

Formula

C₁₀H₁₄F₂N₂O₂

CAS No.

357336-74-4

SMILES

O=C([C@@H](N1C(C[C@H](C1)/C=C(F)\F)=O)CC)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

SeletracetamUcb 44212Ucb44212Ucb-44212OthersSV2AantiepilepticepilepsyInhibitorinhibitorinhibit

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产品名称:
Seletracetam
目录号:
HY-119810
需求量: