2. Gene
  3. Isg15 - ISG15 ubiquitin-like modifier Gene

Isg15 - ISG15 ubiquitin-like modifier Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: G1p2; IP17; Irfp; UCRP; IGI15

基因 ID: 100038882 | 基因类型: protein coding

关于 Isg15

功能概要

Enables protein tag. Involved in several processes, including ISG15-protein conjugation; defense response to Other organism; and positive regulation of erythrocyte differentiation. Acts upstream of or within modification-dependent protein catabolic process and response to bacterium. Predicted to be located in extracellular region. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 38. Orthologous to human ISG15 (ISG15 ubiquitin like modifier). [provided by Alliance of Genome Resources, Apr 2022]

Isg15 基因产物(1)

mRNA Protein Name
NM_015783.3 NP_056598.2 ubiquitin-like protein ISG15
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15485925 MGI
enables protein tag activity IDA
IDA: 通过直接分析推断
16139798 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within ISG15-protein conjugation IDA
IDA: 通过直接分析推断
16139798 MGI
involved in ISG15-protein conjugation IDA
IDA: 通过直接分析推断
22022510 MGI
involved in defense response to bacterium IMP
IMP: 通过突变表型推断
22859821 MGI
involved in defense response to virus IMP
IMP: 通过突变表型推断
17227866 MGI
acts upstream of or within modification-dependent protein catabolic process IDA
IDA: 通过直接分析推断
15485925 MGI
involved in positive regulation of bone mineralization IMP
IMP: 通过突变表型推断
21402791 MGI
involved in positive regulation of erythrocyte differentiation IMP
IMP: 通过突变表型推断
22022510 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ubiquitin-like protein ISG15

interferon, alpha-inducible protein

interferon-induced 15 kDa protein

interferon-induced 15-KDa protein

interferon-induced 17 kDa protein

interferon-stimulated protein (15 kDa)

interferon-stimulated protein 15

ubiquitin cross-reactive protein

Isg15 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Isg15 Q64339 P0C6X7-PRO_0000037311 Human SARS coronavirus P0C6X7-PRO_0000037311
Cleavage
32726803
种属间
Isg15 Q64339 P0C6X7-PRO_0000037311 Human SARS coronavirus P0C6X7-PRO_0000037311
Probe Interaction
32726803
种属间
Isg15 Q64339 P0DTD1-PRO_0000449621 SARS-CoV-2 P0DTD1-PRO_0000449621
Cleavage
32726803
种属间
Isg15 Q64339 P0DTD1-PRO_0000449621 SARS-CoV-2 P0DTD1-PRO_0000449621
X-Ray Diffraction
32726803
种属间
Isg15 Q64339 P0DTD1-PRO_0000449621 SARS-CoV-2 P0DTD1-PRO_0000449621
Protease Assay
32428392
种属间
Isg15 Q64339 P0DTD1-PRO_0000449621 SARS-CoV-2 P0DTD1-PRO_0000449621
Protease Assay
32428392
种属间
Isg15 Q64339 P0DTD1-PRO_0000449621 SARS-CoV-2 P0DTD1-PRO_0000449621
Probe Interaction
32726803
种属内
Isg15 Q64339 Usp18 Mus musculus Q9WTV6
Enzymatic Study
24533902
种属内
Isg15 Q64339 Usp18 Mus musculus Q9WTV6
MST
24533902
种属内
Isg15 Q64339 Usp18 Mus musculus Q9WTV6
Probe Interaction
32726803
种属内
Isg15 Q64339 Usp18 Mus musculus Q9WTV6
Cleavage
32726803
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-172969 ZHAWOC8655 Inhibitor 98.63% 否
HY-152956 STING agonist-23 Agonist 99.33% 否
HY-152959 STING agonist-26 Agonist 99.56% 否
HY-RS06929 ISG15 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-152957 STING agonist-24 Agonist / 否
HY-152958 STING agonist-25 Agonist / 否
HY-152961 STING agonist-28 Agonist / 否
HY-172193 UBD1031 Ligand / 否
HY-174663 Human IFNE mRNA / 否
HY-RS17041 Isg15 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23485 Isg15 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Isg15 NCBI NCBI:9636
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