2. Gene
  3. Abo - ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Gene

Abo - ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Abo2

基因 ID: 100301568 | 基因类型: protein coding

关于 Abo

功能概要

Enables alpha-1,3-galactosyltransferase activity and glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity. Involved in several processes, including cellular oligosaccharide metabolic process; response to nematode; and response to retinoic acid. Located in Golgi apparatus and cytoplasmic vesicle. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; gallbladder carcinoma; leukemia (multiple); lung disease (multiple); and severe acute respiratory syndrome. Orthologous to human ABO (ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Abo 基因产物(1)

mRNA Protein Name
NM_001160263.2 NP_001153735.1 histo-blood group ABO system transferase 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha-1,3-galactosyltransferase activity IDA
IDA: 通过直接分析推断
12626403 RGD
enables glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity IDA
IDA: 通过直接分析推断
11842091 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
12499407 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
12499407 RGD
involved in response to nematode IEP
IEP: 通过表达模式推断
11842091 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
15042712 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histo-blood group ABO system transferase 2

ABO blood group (alpha 1-3-N-acetylgalactosaminyltransferase, alpha 1-3-galactosyltransferase)

ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase

ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase

trans

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70051 alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) / 否
HY-115635 ABO hydrochloride Modulator 98.7% 否
HY-RS00109 ABO Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17181 Abo Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23632 Abo Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abo NCBI NCBI:28
Mus musculus Abo NCBI NCBI:80908
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