1. Gene
  2. Abo - ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase) Gene

Abo - ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase) Gene

种属: Mus musculus

同用名: NAGAT

基因 ID: 80908 | 基因类型: protein coding

关于 Abo

功能概要

Enables fucosylgalactoside 3-alpha-galactosyltransferase activity and glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity. Predicted to be involved in lipid glycosylation. Predicted to be located in cytoplasmic vesicle. Predicted to be active in Golgi apparatus and vesicle. Is expressed in alimentary system; male reproductive gland or organ; and spleen. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; gallbladder carcinoma; leukemia (multiple); lung disease (multiple); and severe acute respiratory syndrome. Orthologous to human ABO (ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Abo 基因产物(2)

mRNA Protein Name
NM_001290444.2 NP_001277373.1 histo-blood group ABO system transferase isoform b
NM_030718.6 NP_109643.3 histo-blood group ABO system transferase isoform a
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fucosylgalactoside 3-alpha-galactosyltransferase activity IDA
IDA: 通过直接分析推断
11278752 MGI
enables glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity IDA
IDA: 通过直接分析推断
11278752 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in oligosaccharide biosynthetic process IDA
IDA: 通过直接分析推断
11278752 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

histo-blood group ABO system transferase

cis-AB transferase

fucosylglycoprotein 3-alpha-galactosyltransferase

fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase

glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase

glycoprotein-fucosylgalactoside alpha-galactosyltr

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abo NCBI NCBI:28
Rattus norvegicus Abo NCBI NCBI:100301568