2. Gene
  3. RBM12 - RNA binding motif protein 12 Gene

RBM12 - RNA binding motif protein 12 Gene

  • 基因
  • 蛋白
  • 疾病
  • 直系同源

中文名称：RNA 结合基序蛋白 12

种属: Homo sapiens

同用名: SWAN; SCZD19; HRIHFB2091

基因 ID: 10137 | 基因类型: protein coding

关于 RBM12

Cytogenetic location: 20q11.22 Genomic coordinates (GRCh38): 20:35,648,925-35,664,900 (from NCBI)

This gene has 6 transcripts (splice variants), 126 orthologues, 8 paralogues and is associated with 1 phenotype. Ubiquitous expression in lymph node (RPKM 14.4), ovary (RPKM 12.2) and 25 other tissues.

功能概要

该基因编码的蛋白质包含多个 RNA 结合基序、潜在的跨膜结构域和富含脯氨酸的区域。该基因和 copine I 的基因在图谱位置 20q11.21 重叠。 5' UTR 中的可变剪接导致四种转录本变体。所有变体编码相同的蛋白质。[RefSeq 提供，2010 年 11 月]

This gene encodes a protein that contains several RNA-binding motifs, potential transmembrane domains, and proline-rich regions. This gene and the gene for copine I overlap at map location 20q11.21. Alternative splicing in the 5' UTR results in four transcript variants. All variants encode the same protein. [provided by RefSeq, Nov 2010]

RBM12 基因产物(4)

mRNA Protein Name
NM_001198838.2 NP_001185767.1 RNA-binding protein 12
NM_001198840.2 NP_001185769.1 RNA-binding protein 12
NM_006047.6 NP_006038.2 RNA-binding protein 12
NM_152838.4 NP_690051.1 RNA-binding protein 12

RBM12 蛋白结构

(5 - 69)

(307 - 372)

(432 - 501)

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (548 - 613)

(859 - 928)

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  • 932 a.a.
蛋白主名 其他名称

RNA-binding protein 12

SH3/WW domain anchor protein in the nucleus

关联疾病

疾病名称 别名
Schizophrenia 19

SCZD19

Schizophrenia 19 With Or Without An Affective Disorder

Schizophrenia 19, Susceptibility To

{Schizophrenia 19, Susceptibility To}
Schizoaffective Disorder

Schizo-Affective Psychosis

Schizo-Affective Type Schizophrenia

Schizoaffective Psychosis

Schizoaffective Schizophrenia

Schizophrenia, Schizo-Affective Type

Schizophreniform Psychosis, Affective Type
Psychotic Disorder

Psychotic Disorders

Mental Or Behavioural Disorder

Psychotic

Mental Disorders
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus RBM12 MGD MGI:1922960
Canis familiaris RBM12 VGNC VGNC:45406
Rattus norvegicus RBM12 RGD RGD:1594333
Bos taurus RBM12 VGNC VGNC:33785