1. Gene
  2. Vrk3 - vaccinia related kinase 3 Gene

Vrk3 - vaccinia related kinase 3 Gene

种属: Mus musculus

基因 ID: 101568 | 基因类型: protein coding

关于 Vrk3

功能概要

Enables protein Phosphatase binding activity. Acts upstream of or within negative regulation of ERK1 and ERK2 cascade and positive regulation of phosphoprotein Phosphatase activity. Located in nucleus. Is expressed in several structures, including dorsal mesogastrium; hemolymphoid system; liver; metanephros; and yolk sac. Used to study autism spectrum disorder. Orthologous to human VRK3 (VRK serine/threonine kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Vrk3 基因产物(1)

mRNA Protein Name
NM_133945.1 NP_598706.1 inactive serine/threonine-protein kinase VRK3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein phosphatase activator activity IPI
IPI: 通过物理相互作用推断
18035061 MGI
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
18035061 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
18035061 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
14645249 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

inactive serine/threonine-protein kinase VRK3

serine/threonine-protein kinase VRK3

serine/threonine-protein pseudokinase VRK3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vrk3 NCBI NCBI:51231