2. Gene
  3. CTDSPL - CTD small phosphatase like Gene

CTDSPL - CTD small phosphatase like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：CTD 小磷酸酶样

种属: Homo sapiens

同用名: PSR1; SCP3; HYA22; RBSP3; C3orf8

基因 ID: 10217 | 基因类型: protein coding

关于 CTDSPL

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:37,861,880-37,984,469 (from NCBI)

This gene has 8 transcripts (splice variants), 254 orthologues and 5 paralogues. Ubiquitous expression in skin (RPKM 20.1), gall bladder (RPKM 14.9) and 25 other tissues.

功能概要

预测能使 RNA 聚合酶 II CTD 七肽重复磷酸酶活性。预测参与蛋白质去磷酸化。预计在有丝分裂细胞周期 G1/S 转换的负调节和蛋白质磷酸化的负调节的上游或内部起作用。位于细胞外外泌体。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable RNA polymerase II CTD heptapeptide repeat Phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to act upstream of or within negative regulation of G1/S transition of mitotic cell cycle and negative regulation of protein phosphorylation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

CTDSPL 基因产物(2)

mRNA Protein Name
NM_001008392.2 NP_001008393.1 CTD small phosphatase-like protein isoform 1
NM_005808.3 NP_005799.2 CTD small phosphatase-like protein isoform 2

CTDSPL 蛋白结构

NIF

NIF: NLI interacting factor-like phosphatase (107 - 266)

  • 0
  • 100
  • 200
  • 276 a.a.
蛋白主名 其他名称

CTD small phosphatase-like protein

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

关联疾病

疾病名称 别名
Granulomatous Disease, Chronic, Autosomal Recessive, 2

Chronic Granulomatous Disease Due To Deficiency Of Ncf-2

CGD2

Ncf2 Deficiency

P67-Phox Deficiency

Autosomal Recessive Chronic Granulomatous Disease Cytochrome B-Positive Type Ii

Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type 2

Granulomatous Disease, Chronic, Autosomal Recessive, Cytochrome B-Positive, Type Ii

Cgd, Autosomal Recessive Cytochrome B-Positive, Type Ii

Granulomatous Disease, Chronic, Due To Ncf2 Deficiency

Neutrophil Cytosol Factor 2 Deficiency

Chronic Granulomatous Disease 2, Autosomal Recessive

Autosomal Recessive Chronic Granulomatous Disease 2

Cdg2

Deficiency Of Ncf2

Deficiency Of P67-Phox

Chronic Granulomatous Disease Autosomal Recessive Cytochrome B-Positive Type Ii

Deficiency Of Neutrophil Cytosol Factor 2

Avellino Corneal Dystrophy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158820 Cosdosiran / 否
HY-158820A Cosdosiran sodium / 否
HY-E70364 IgdE protease / 否
HY-RS03293 CTDSPL Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS03294 CTDSPL2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta CTDSPL VGNC VGNC:71425
Rattus norvegicus CTDSPL RGD RGD:1304841
Bos taurus CTDSPL VGNC VGNC:106702
Felis catus CTDSPL VGNC VGNC:61249
Mus musculus CTDSPL MGD MGI:1916524
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