2. Gene
  3. GLYAT - glycine-N-acyltransferase Gene

GLYAT - glycine-N-acyltransferase Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：甘氨酸-N-酰基转移酶

种属: Homo sapiens

同用名: CAT; GAT; ACGNAT

基因 ID: 10249 | 基因类型: protein coding

关于 GLYAT

Cytogenetic location: 11q12.1 Genomic coordinates (GRCh38): 11:58,708,757-58,731,943 (from NCBI)

This gene has 6 transcripts (splice variants), 227 orthologues and 4 paralogues. Biased expression in kidney (RPKM 86.1), liver (RPKM 53.7) and 1 other tissue.

功能概要

甘氨酸-N-酰基转移酶蛋白使甘氨酸与线粒体中的酰基辅酶 A 底物结合。该蛋白质被认为在内源性和外源性酰基辅酶 A 的解毒中很重要。已发现该基因的两个转录本变体编码不同的亚型。[RefSeq 提供，2008 年 7 月]

The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GLYAT 基因产物(2)

mRNA Protein Name
NM_005838.4 NP_005829.3 glycine N-acyltransferase isoform b
NM_201648.3 NP_964011.2 glycine N-acyltransferase isoform a

GLYAT 蛋白结构

Gly_acyl_tr_N

Gly_acyl_tr_N: Aralkyl acyl-CoA:amino acid N-acyltransferase (2 - 206)

Gly_acyl_tr_C

Gly_acyl_tr_C: Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region (207 - 295)

  • 0
  • 100
  • 200
  • 296 a.a.
蛋白主名 其他名称

glycine N-acyltransferase

AAc

关联疾病

疾病名称 别名
Osteogenesis Imperfecta, Type I

Osteogenesis Imperfecta Type I

OI1

Oi, Type I

Osteogenesis Imperfecta Tarda

Osteogenesis Imperfecta With Blue Sclerae

Osteogenesis Imperfecta Type 1

Adair-Dighton Syndrome

Mild Osteogenesis Imperfecta

Non-Deforming Osteogenesis Imperfecta

Oi Type 1

Van Der Hoeve Syndrome

Classic Non-Deforming Oi With Blue Sclerae

Osteogenesis Imperfecta 1

Oi-I

Osteopenic Non-Fracture Syndrome

Osteogenesis Imperfecta, Mild

Osteogenesis Imperfecta

Lobstein'S Disease
Adenosquamous Prostate Carcinoma

Adenosquamous Carcinoma Of Prostate

Adenosquamous Carcinoma Of The Prostate
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158820 Cosdosiran / 否
HY-158820A Cosdosiran sodium / 否
HY-E70364 IgdE protease / 否
HY-RS05510 GLYAT Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GLYAT RGD RGD:1307163
Canis familiaris GLYAT VGNC VGNC:97198
Macaca mulatta GLYAT VGNC VGNC:72937
Mus musculus GLYAT MGD MGI:2147502
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