1. Gene
  2. CCL26 - C-C motif chemokine ligand 26 Gene

CCL26 - C-C motif chemokine ligand 26 Gene

中文名称:CC 基序趋化因子配体 26

种属: Homo sapiens

同用名: IMAC; TSC-1; MIP-4a; SCYA26; MIP-4alpha

基因 ID: 10344 | 基因类型: protein coding

关于 CCL26

Cytogenetic location: 7q11.23 Genomic coordinates (GRCh38): 7:75,769,524-75,791,597 (from NCBI)

This gene has 2 transcripts (splice variants), 81 orthologues and 25 paralogues. Broad expression in ovary (RPKM 2.0), adrenal (RPKM 0.7) and 14 other tissues.


该基因是聚集在 7 号染色体 q 臂上的两个 Cys-Cys (CC) 细胞因子基因之一。细胞因子是参与免疫调节和炎症过程的分泌蛋白家族。 CC 细胞因子是以两个相邻的半胱氨酸为特征的蛋白质。由该基因编码的细胞因子显示出对正常外周血嗜酸性粒细胞和嗜碱性粒细胞的趋化活性。这种蛋白质还具有抗菌活性,对肺炎链球菌、金黄色葡萄球菌、不可分型流感嗜血杆菌和铜绿假单胞菌显示出抗菌作用。该基因的产物是特异性激活趋化因子受体 CCR3 的三种相关趋化因子之一。这种趋化因子可能有助于特应性疾病中嗜酸性粒细胞的积累。[RefSeq 提供,2020 年 7 月]

This gene is one of two Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 7. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for normal peripheral blood eosinophils and basophils. This protein also has antimicrobial activity, displaying an Antibacterial effect on S. pneumoniae, S. aureus, Non-typeable H. influenzae, and P. aeruginosa. The product of this gene is one of three related chemokines that specifically activate Chemokine Receptor CCR3. This chemokine may contribute to the eosinophil accumulation in atopic diseases. [provided by RefSeq, Jul 2020]

CCL26 基因产物(3)

mRNA Protein Name
NM_001371936.1 NP_001358865.1 C-C motif chemokine 26 precursor
NM_001371938.1 NP_001358867.1 C-C motif chemokine 26 precursor
NM_006072.4 NP_006063.1 C-C motif chemokine 26 precursor

CCL26 蛋白结构


IL8: Small cytokines (intecrine/chemokine), interleukin-8 like (30 - 86)

  • 0
  • 94 a.a.
蛋白主名 其他名称

C-C motif chemokine 26

CC chemokine IMAC

重组 CCL26 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7163 Eotaxin-3/CCL26 Protein, Human Q9Y258 (T24-L94) ≥95%
HY-P75606 Eotaxin-3/CCL26 Protein, Human (sf9) Q9Y258 (M1-L94) ≥95%


疾病名称 别名

Acute Esophagitis

Heart Tumor

Intracavitary Tumors

Myocardial Tumors

Primary Cardiac Tumors, Childhood

Heart Neoplasm

Intracavitary Tumors Of The Heart

Neoplasm Of Myocardium

Churg-Strauss Syndrome

Eosinophilic Granulomatosis With Polyangiitis

Allergic Granulomatous Angiitis

Churg-Strauss Vasculitis

Allergic Angiitis


Granulomatous Allergic Angiitis

Allergic Granulomatosis Angiitis

Allergic Angiitis And Granulomatosis

Allergic Granulomatosis

Allergic Granulomatous And Angiitis


Tuberous Sclerosis

Tuberous Sclerosis Syndrome

Bourneville'S Disease


Cerebral Sclerosis

Tuberose Sclerosis

Tuberous Sclerosis 1

Bourneville Disease

Bourneville Phakomatosis

Pringle'S Disease

Eosinophilic Gastritis

Eosinophilic Enteropathy


Angiomyolipoma Of Kidney

Congenital Heart Defects, Hamartomas Of Tongue, And Polysyndactyly

Ostravik-Lindemann-Solberg Syndrome


Heart Defect-Tongue Hamartoma-Polysyndactyly Syndrome

Orstavik Lindemann Solberg Syndrome

Heart Defect - Tongue Hamartoma - Polysyndactyly Syndrome

Heart Defect, Tongue Hamartoma And Polysyndactyly


Tuberous Sclerosis 1

Tuberous Sclerosis Complex

Tuberous Sclerosis

Bourneville Syndrome


Tuberose Sclerosis


Tuberous Sclerosis-1

Bourneville Disease


Bourneville Phakomatosis

Cerebral Sclerosis

Sclerosis Tuberosa

Tuberous Sclerosis, Type 1

Allergic Asthma

Atopic Asthma

Extrinsic Asthma

Extrinsic Asthma With Acute Exacerbation

Extrinsic Asthma With Status Asthmaticus

Asthma Allergic

Atopic Asthma, Susceptibility To

Ige-Mediated Allergic Asthma

Allergen-Induced Asthma

Allergic Asthma Without Stated Status Asthmaticus

Predominantly Allergic Asthma Without Stated Status Asthmaticus

Predominantly Allergic Asthma

Allergic Asthma Nos

Catarrh With Asthma

Allergic Bronchitis Nos

Extrinsic Allergic Asthma

Predominantly Allergic Asthma With Stated Status Asthmaticus

Esophagitis, Eosinophilic, 1

Eosinophilic Esophagitis


Esophagitis, Eosinophilic


Gastroesophageal Reflux

Gastroesophageal Reflux Disease



Gastroesophageal Reflux, Pediatric

Acid Reflux

Gastresophageal Reflux

Gastro-Esophageal Reflux

Gerd - Gastro-Esophageal Reflux Disease

Hypereosinophilic Syndrome



Eosinophilic Leukocytosis

Hypereosinophilic Syndrome, Idiopathic

Idiopathic Hypereosinophilic Syndrome

Disseminated Eosinophilic Collagen Disease

Eosinophilic Disorder

Disorders With Increased Eosinophil Counts

Eosinophilic Gastroenteritis

Eosinophilic Enteritis


Eosinophilic Gastroenterocolitis

Eosinophilic Esophagitis

Eosinophilic Gastritis

Eosinophilic Gastroenteropathy

Gastroenteritis, Eosinophilic

Eosinophilic Enteropathy

Esophageal Candidiasis

Candidiasis Of The Esophagus

Candida Esophagitis

Candidal Esophagitis

Esophageal Moniliasis

Esophageal Thrush

Dyskinesia Of Esophagus

Esophageal Motility Disorders

Dyskinesia Of Oesophagus

Esophageal Dysmotility

Esophageal Motility Disorder

Oesophageal Dysmotility

Oesophageal Motor Disorder

Esophageal Spasm


Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus


Monkeypox Virus Infections

Peptic Esophagitis

Reflux Esophagitis

Peptic Reflux Disease

Reflux Oesophagitis

Esophagitis, Peptic

Gastro-Esophageal Reflux Disease With Esophagitis

Abcd Syndrome


Albinism, Black Lock, Cell Migration Disorder Of The Neurocytes Of The Gut, And Deafness

Albinism, Black Lock, Cell Migration Disorder Of The Neurocytes Of The Gut And Deafness

Cystic Kidney Disease

Renal Cyst

Simple Renal Cyst

Kidney Cysts

Kidney Diseases, Cystic

Renal Cysts

Kidney Cyst

Cystic Kidney

Congenital Cystic Kidney Disease

Cystic Kidney Diseases

Bosniak 1 Cyst

Endomyocardial Fibrosis

Becker'S Disease

Obscure African Cardiomyopathy

African Endomyocardial Fibrosis

Endomyocardial Sclerosis


Becker Muscular Dystrophy

Nasal Cavity Disease

Disorder Of Nasal Cavity

Nose Disease

Nose Diseases

Disorder Of The Nose

Nasal Disorder

Abnormality Of The Nose

Respiratory Allergy

Airway Allergy

Common Cold

Acute Coryza

Acute Nasopharyngitis

Acute Rhinitis

Acute Viral Rhinopharyngitis

Nasopharyngitis - Acute

Nasopharyngitis, Acute



Common Colds

Acute Infective Rhinitis



Head Cold

Infective Nasopharyngitis


Acute Nasal Catarrh

Infective Rhinitis

Acute Nasopharyngeal Catarrh

Infective Nasopharyngitis Nos

Nasopharyngitis Nos


Mucositis Nos

Inflammatory Disease Of Mucous Membrane

Mucosal Inflammation

Contact Dermatitis

Contact Dermatitis/Eczema

Contact Eczema

Dermatitis Venenata

Dermatitis, Venenata

Dermatitis Contact

Dermatitis, Contact

Bronchial Disease

Bronchial Diseases

Bronchial Disorders

Bronchial Spasm

Granulomatosis With Polyangiitis


Wegener Granulomatosis

Wegener Granulomatosis, Formerly

Midline Granulomatosis

Wg, Formerly

Necrotizing Respiratory Granulomatosis


Wegeners Granulomatosis

Pauci-Immune Glomerulonephritis Associated With Granulomatosis With Polyangiitis

Polycystic Kidney Disease

Polycystic Kidney Diseases


Polycystic Renal Disease

Kidney Disease, Polycystic

Polycystic Kidney, Autosomal Dominant

Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1


Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic


Besnier Prurigo

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma


种属 基因名 来源 基因 ID
Mus musculus CCL26 MGD MGI:3589281
Canis familiaris CCL26 VGNC VGNC:38888
Bos taurus CCL26 VGNC VGNC:106677
Felis catus CCL26 VGNC VGNC:107744
Macaca mulatta CCL26 VGNC VGNC:70701
Rattus norvegicus CCL26 RGD RGD:1587817
Others CCL26 NCBI