2. Gene
  3. CLEC10A - C-type lectin domain containing 10A Gene

CLEC10A - C-type lectin domain containing 10A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含 C 型凝集素结构域 10A

种属: Homo sapiens

同用名: HML; MGL; HML2; CD301; CLECSF13; CLECSF14

基因 ID: 10462 | 基因类型: protein coding

关于 CLEC10A

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,074,537-7,080,251 (from NCBI)

This gene has 6 transcripts (splice variants), 148 orthologues and 14 paralogues. Broad expression in appendix (RPKM 13.9), small intestine (RPKM 10.3) and 21 other tissues.

功能概要

该基因编码 C 型凝集素/C 型凝集素样结构域 (CTL/CTLD) 超家族的成员。该家族的成员具有共同的蛋白质折叠并具有多种功能，例如细胞粘附、细胞间信号传导、糖蛋白转换以及在炎症和免疫反应中的作用。编码的 2 型跨膜蛋白可作为细胞表面抗原发挥作用。已经为该基因鉴定了编码不同亚型的两个转录物变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

CLEC10A 基因产物(3)

mRNA Protein Name
NM_001330070.2 NP_001316999.1 C-type lectin domain family 10 member A isoform 3
NM_006344.4 NP_006335.2 C-type lectin domain family 10 member A isoform 2
NM_182906.4 NP_878910.1 C-type lectin domain family 10 member A isoform 1

CLEC10A 蛋白结构

Lectin_N

Lectin_N: Hepatic lectin, N-terminal domain (7 - 128)

Lectin_C

Lectin_C: Lectin C-type domain (199 - 305)

  • 0
  • 100
  • 200
  • 316 a.a.
蛋白主名 其他名称

C-type lectin domain family 10 member A

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived)

重组 CLEC10A 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72689 CLEC10A/CD301 Protein, Human (HEK293, His) Q8IUN9 (Q61-H316) ≥95%
HY-P75676 CLEC10A/CD301 Protein, Human (HEK293, Fc) Q8IUN9-2 (Q61-H292) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02779 CLEC10A Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus CLEC10A VGNC VGNC:55799
Rattus norvegicus CLEC10A RGD RGD:621158
Macaca mulatta CLEC10A VGNC VGNC:71188
Mus musculus CLEC10A NCBI
Others CLEC10A NCBI
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