2. Gene
  3. Cbll1 - Casitas B-lineage lymphoma-like 1 Gene

Cbll1 - Casitas B-lineage lymphoma-like 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Hakai; c-Cbl-like

基因 ID: 104836 | 基因类型: protein coding

关于 Cbll1

功能概要

Enables identical protein binding activity and ubiquitin protein Ligase activity. Acts upstream of or within negative regulation of cell adhesion; positive regulation of cell migration; and positive regulation of endocytosis. Located in cytoplasm and nucleus. Part of RNA N6-methyladenosine methyltransferase complex. Is expressed in heart ventricle. Orthologous to human CBLL1 (Cbl proto-oncogene like 1). [provided by Alliance of Genome Resources, Apr 2022]

Cbll1 基因产物(3)

mRNA Protein Name
NM_001253847.1 NP_001240776.1 E3 ubiquitin-protein ligase Hakai isoform 1
NM_001253848.1 NP_001240777.1 E3 ubiquitin-protein ligase Hakai isoform 3
NM_134048.2 NP_598809.1 E3 ubiquitin-protein ligase Hakai isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
22252131 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11836526 MGI
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
11836526 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of cell adhesion IDA
IDA: 通过直接分析推断
11836526 MGI
acts upstream of or within positive regulation of cell migration IDA
IDA: 通过直接分析推断
11836526 MGI
acts upstream of or within positive regulation of endocytosis IDA
IDA: 通过直接分析推断
11836526 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA N6-methyladenosine methyltransferase complex IDA
IDA: 通过直接分析推断
29547716 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
29547716 MGI
located in nucleus IDA
IDA: 通过直接分析推断
29547716 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase Hakai

E-cadherin binding protein E7

RING-type E3 ubiquitin transferase Hakai

c-Cbl-like protein 1

casitas B-lineage lymphoma-transforming sequence-like protein 1

Cbll1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Cbll1 Q9JIY2 DOK1 Homo sapiens Q99704
Competition Binding
22252131
种属间
Cbll1 Q9JIY2 DOK1 Homo sapiens Q99704
Anti Tag CoIP
22252131
种属间
Cbll1 Q9JIY2 CTTN Homo sapiens Q14247
Anti Tag CoIP
22252131
种属内
Cbll1 Q9JIY2 Cttn Mus musculus Q60598
Anti Tag CoIP
22252131
种属间
Cbll1 Q9JIY2 CDH1 Homo sapiens P12830
Pull Down
22252131
种属间
Cbll1 Q9JIY2 CDH1 Homo sapiens P12830
NMR
22252131
种属内
Cbll1 Q9JIY2 CDH1 Homo sapiens P12830
Anti Tag CoIP
22252131
种属间
Cbll1 Q9JIY2 CDH1 Homo sapiens P12830
ITC
22252131
种属内
Cbll1 Q9JIY2 Cbll1 Mus musculus Q9JIY2
X-Ray Diffraction
22252131
种属内
Cbll1 Q9JIY2 Cbll1 Mus musculus Q9JIY2
GMS
22252131
种属内
Cbll1 Q9JIY2 Cbll1 Mus musculus Q9JIY2
DLS
22252131
种属内
Cbll1 Q9JIY2 Cbll1 Mus musculus Q9JIY2
Anti Tag CoIP
22252131
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02000 CBLL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20871 Cbll1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27388 Cbll1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cbll1 NCBI NCBI:79872
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