2. Gene
  3. Mycbp2 - MYC binding protein 2, E3 ubiquitin protein ligase Gene

Mycbp2 - MYC binding protein 2, E3 ubiquitin protein ligase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pam; Phr1; C130061D10Rik

基因 ID: 105689 | 基因类型: protein coding

关于 Mycbp2

功能概要

Enables identical protein binding activity. Involved in several processes, including central nervous system projection neuron axonogenesis; circadian regulation of gene expression; and positive regulation of protein ubiquitination. Acts upstream of or within several processes, including branchiomotor neuron axon guidance; negative regulation of protein catabolic process; and regulation of Cytoskeleton organization. Located in axon and microtubule Cytoskeleton. Is expressed in nervous system and neural retina. Orthologous to human MYCBP2 (MYC binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Mycbp2 基因产物(1)

mRNA Protein Name
NM_207215.2 NP_997098.2 E3 ubiquitin-protein ligase MYCBP2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12522145 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within branchiomotor neuron axon guidance IMP
IMP: 通过突变表型推断
18031680 MGI
acts upstream of or within cell morphogenesis involved in neuron differentiation IMP
IMP: 通过突变表型推断
18031680 MGI
acts upstream of or within central nervous system projection neuron axonogenesis IMP
IMP: 通过突变表型推断
18031680 MGI
involved in central nervous system projection neuron axonogenesis IMP
IMP: 通过突变表型推断
17901218 MGI
involved in circadian regulation of gene expression IMP
IMP: 通过突变表型推断
20534529 MGI
acts upstream of or within motor neuron axon guidance IMP
IMP: 通过突变表型推断
18031680 MGI
acts upstream of or within negative regulation of protein catabolic process IDA
IDA: 通过直接分析推断
19398581 MGI
involved in neuromuscular process IMP
IMP: 通过突变表型推断
17901218 MGI
involved in positive regulation of protein ubiquitination IDA
IDA: 通过直接分析推断
20534529 MGI
involved in regulation of axon guidance IMP
IMP: 通过突变表型推断
17901218 MGI
acts upstream of or within regulation of cytoskeleton organization IMP
IMP: 通过突变表型推断
18031680 MGI
acts upstream of or within regulation of protein localization IMP
IMP: 通过突变表型推断
18031680 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
18031680 MGI
located in microtubule cytoskeleton IDA
IDA: 通过直接分析推断
18031680 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase MYCBP2

Myc-binding protein 2

RING-type E3 ubiquitin transferase MYCBP2

pam, highwire, rpm 1

pam/highwire/rpm-1 protein

probable E3 ubiquitin-protein ligase MYCBP2

protein Magellan

protein associated with Myc

Mycbp2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Mycbp2 Q7TPH6 Slc12a5 Rattus norvegicus Q63633
Pull Down
18769030
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08881 MYCBP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21160 Mycbp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27676 Mycbp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mycbp2 NCBI NCBI:23077
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