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  2. YKT6 - YKT6 v-SNARE homolog Gene

YKT6 - YKT6 v-SNARE homolog Gene

中文名称:YKT6 v-SNARE 同系物

种属: Homo sapiens

基因 ID: 10652 | 基因类型: protein coding

关于 YKT6

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:44,200,978-44,214,294 (from NCBI)

This gene has 15 transcripts (splice variants), 232 orthologues and 10 paralogues. Ubiquitous expression in brain (RPKM 24.8), colon (RPKM 21.7) and 25 other tissues.

功能概要

该基因产物是涉及分泌区室之间囊泡转运的 SNARE 识别分子之一。它是一种膜相关的异戊二烯化蛋白质,在内质网-高尔基体转运步骤中发挥作用。这种蛋白质从酵母到人类高度保守,可以在功能上补充酵母分泌途径中酵母同系物的缺失。[RefSeq 提供,2008 年 7 月]

This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway. [provided by RefSeq, Jul 2008]

YKT6 基因产物(3)

mRNA Protein Name
NM_001363678.2 NP_001350607.1 synaptobrevin homolog YKT6 isoform 2
NM_001410874.1 NP_001397803.1 synaptobrevin homolog YKT6 isoform 3
NM_006555.4 NP_006546.1 synaptobrevin homolog YKT6 isoform 1

YKT6 蛋白结构

Longin

Longin: Regulated-SNARE-like domain (44 - 106)

Synaptobrevin

Synaptobrevin: Synaptobrevin (136 - 192)

  • 0
  • 100
  • 198 a.a.
蛋白主名 其他名称

synaptobrevin homolog YKT6

R-SNARE

重组 YKT6 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71025 YKT6 Protein, Human (His) O15498 (M1-M198) ≥95%

关联疾病

疾病名称 别名
Foodborne Botulism

Botulism

Botulism Poisoning

Intoxication With Clostridium Botulinum Toxin

Wound Botulism

Food Poisoning Due To Clostridium Botulinum

Infection Due To Clostridium Botulinum

Infant Botulism

Intoxication Botulism

Botulism, Infantile

Clostridium Botulinum Poisoning

Botulism Nos

Infant Botulism

Infant Intestinal Botulism

Infant Intestinal Toxemia Botulism

Infant Intestinal Toxin-Mediated Botulism

Infantile Botulism

Botulism, Infantile

Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome

Cednik Syndrome

CEDNIK

Cerebral Dysgenesis, Neuropathy, Ichthyosis And Keratoderma Syndrome

Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndro

Cerebral Dysgenesis-Neuropathy-Ichthyosis-Palmoplantar Keratoderma Syndrome

Cerebral Dysgenesis-Neuropathy-Ichthyosis-Keratoderma Syndrome

Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma

Neurocutaneous Syndromes

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus YKT6 VGNC VGNC:37030
Mus musculus YKT6 MGD MGI:1927550
Macaca mulatta YKT6 VGNC VGNC:81796
Felis catus YKT6 VGNC VGNC:67146
Rattus norvegicus YKT6 RGD RGD:70897
Others YKT6 NCBI