YKT6 蛋白, Human (His)

YKT6 is a vesicle soluble NSF attachment protein receptor (v-SNARE) that mediates vesicle docking and fusion in the endoplasmic reticulum to Golgi trafficking, forming a SNARE complex with GOSR1, GOSR2, and STX5. It is also involved in the transport of early/recycling endosomes to the trans-Golgi network, forming another SNARE complex with BET1L, GOSR1 and STX5. YKT6 Protein, Human (His) is the recombinant human-derived YKT6 protein, expressed by E. coli , with N-6*His labeled tag. The total length of YKT6 Protein, Human (His) is 198 a.a., with molecular weight of ~28.0 kDa.

YKT6 是一种囊泡可溶性 NSF 附着蛋白受体 (v-SNARE)，在介导囊泡与特定受体细胞区室对接和融合方面发挥着关键作用。它在内质网中向高尔基体运输发挥作用，与 GOSR1、GOSR2 和 STX5 一起形成 SNARE 复合体。此外，YKT6 参与早期/再循环内体到高尔基体网络的转运，与 BET1L、GOSR1 和 STX5 形成另一个 SNARE 复合体。除了在膜融合事件中的作用之外，YKT6 还表现出 S-棕榈酰转移酶活性，为其功能库增加了一层复杂性。YKT6 在两个不同的 SNARE 复合体中被鉴定出来，它的参与强调了它在细胞运输网络内协调囊泡运输和膜融合过程中的重要性。

Human

E. coli

N-6*His

O15498 (M1-M198)

10652  [NCBI]

MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM

Approximately 28.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 50 mM Tris, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.