2. Gene
  3. ZMYND11 - zinc finger MYND-type containing 11 Gene

ZMYND11 - zinc finger MYND-type containing 11 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含锌指 MYND 型 11

种属: Homo sapiens

同用名: BS69; BRAM1; MRD30

基因 ID: 10771 | 基因类型: protein coding

关于 ZMYND11

Cytogenetic location: 10p15.3 Genomic coordinates (GRCh38): 10:130,088-254,637 (from NCBI)

This gene has 26 transcripts (splice variants), 212 orthologues, 5 paralogues and is associated with 3 phenotypes. Ubiquitous expression in thyroid (RPKM 38.3), brain (RPKM 25.5) and 25 other tissues.

功能概要

由该基因编码的蛋白质首先通过其结合腺病毒 E1A 蛋白的能力得到鉴定。蛋白质定位于细胞核。它起转录抑制因子的作用，E1A 的表达会抑制这种抑制作用。已经鉴定出编码不同亚型的选择性剪接转录物变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

ZMYND11 基因产物(36)

mRNA Protein Name
NM_001202464.3 NP_001189393.1 zinc finger MYND domain-containing protein 11 isoform c
NM_001202465.3 NP_001189394.1 zinc finger MYND domain-containing protein 11 isoform d
NM_001202466.3 NP_001189395.1 zinc finger MYND domain-containing protein 11 isoform e
NM_001202467.1 NP_001189396.1 zinc finger MYND domain-containing protein 11 isoform f
NM_001202468.1 NP_001189397.1 zinc finger MYND domain-containing protein 11 isoform g
NM_001330057.3 NP_001316986.1 zinc finger MYND domain-containing protein 11 isoform h
NM_001370097.3 NP_001357026.1 zinc finger MYND domain-containing protein 11 isoform a
NM_001370098.2 NP_001357027.1 zinc finger MYND domain-containing protein 11 isoform a
NM_001370099.2 NP_001357028.1 zinc finger MYND domain-containing protein 11 isoform a
NM_001370100.5 NP_001357029.1 zinc finger MYND domain-containing protein 11 isoform a
NM_001370101.2 NP_001357030.1 zinc finger MYND domain-containing protein 11 isoform a
NM_001370102.2 NP_001357031.1 zinc finger MYND domain-containing protein 11 isoform a
NM_001370103.2 NP_001357032.1 zinc finger MYND domain-containing protein 11 isoform c
NM_001370104.2 NP_001357033.1 zinc finger MYND domain-containing protein 11 isoform c
NM_001370105.2 NP_001357034.1 zinc finger MYND domain-containing protein 11 isoform c
NM_001370106.2 NP_001357035.1 zinc finger MYND domain-containing protein 11 isoform c
NM_001370107.2 NP_001357036.1 zinc finger MYND domain-containing protein 11 isoform c
NM_001370108.2 NP_001357037.1 zinc finger MYND domain-containing protein 11 isoform c
NM_001370109.2 NP_001357038.1 zinc finger MYND domain-containing protein 11 isoform c
NM_001370110.2 NP_001357039.1 zinc finger MYND domain-containing protein 11 isoform d
NM_001370111.2 NP_001357040.1 zinc finger MYND domain-containing protein 11 isoform e
NM_001370112.2 NP_001357041.1 zinc finger MYND domain-containing protein 11 isoform h
NM_001370113.2 NP_001357042.1 zinc finger MYND domain-containing protein 11 isoform i
NM_001370114.2 NP_001357043.1 zinc finger MYND domain-containing protein 11 isoform i
NM_001370115.2 NP_001357044.1 zinc finger MYND domain-containing protein 11 isoform j
NM_001370116.2 NP_001357045.1 zinc finger MYND domain-containing protein 11 isoform k
NM_001370117.2 NP_001357046.1 zinc finger MYND domain-containing protein 11 isoform l
NM_001370118.2 NP_001357047.1 zinc finger MYND domain-containing protein 11 isoform m
NM_001370119.2 NP_001357048.1 zinc finger MYND domain-containing protein 11 isoform n
NM_001370120.2 NP_001357049.1 zinc finger MYND domain-containing protein 11 isoform o
NM_001370121.2 NP_001357050.1 zinc finger MYND domain-containing protein 11 isoform p
NM_001370122.2 NP_001357051.1 zinc finger MYND domain-containing protein 11 isoform q
NM_001370123.2 NP_001357052.1 zinc finger MYND domain-containing protein 11 isoform r
NM_001370124.3 NP_001357053.1 zinc finger MYND domain-containing protein 11 isoform s
NM_006624.7 NP_006615.2 zinc finger MYND domain-containing protein 11 isoform a
NM_212479.4 NP_997644.2 zinc finger MYND domain-containing protein 11 isoform b

ZMYND11 蛋白结构

Bromodomain

Bromodomain: Bromodomain (182 - 242)

PWWP

PWWP: PWWP domain (281 - 351)

  • 0
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  • 500
  • 602 a.a.
蛋白主名 其他名称

zinc finger MYND domain-containing protein 11

adenovirus 5 E1A-binding protein

关联疾病

疾病名称 别名
Intellectual Developmental Disorder, Autosomal Dominant 30, With Speech Delay And Behavioral Abnormalities

MRD30

Mental Retardation, Autosomal Dominant 30

Intellectual Developmental Disorder, Autosomal Dominant 30

Autosomal Dominant Non-Syndromic Intellectual Disability 30

Autosomal Dominant Intellectual Developmental Disorder 30

Autosomal Dominant Mental Retardation 30

Mental Retardation, Autosomal Dominant, Type 30
Autosomal Dominant Intellectual Disability 30

Intellectual Disability, Autosomal Dominant 30
Autosomal Dominant Non-Syndromic Intellectual Disability
Fibrodysplasia Ossificans Progressiva

Myositis Ossificans Progressiva

Progressive Myositis Ossificans

FOP

Progressive Ossifying Myositis

Myositis Ossificans

Stone Man Syndrome

Man Of Stone

Myositis Ossificans Progressive

Diffuse Progressive Ossifying Polymyositis

Fibrodysplasia Ossificans Congenita

Myositis Ossificans Progressiva, Site Unspecified

Münchmeyer Disease

Fop - [Fibrodysplasia Ossificans Progressiva]

Progressive Myositis Ossificans Calcification
Hypoparathyroidism-Deafness-Renal Disease Syndrome

Barakat Syndrome

Hypoparathyroidism, Deafness, Renal Disease Syndrome

Hdr Syndrome

Hypoparathyroidism, Sensorineural Deafness, And Renal Disease
Familial Cold Autoinflammatory Syndrome 3

Plaid

Familial Atypical Cold Urticaria

Facu

FCAS3

Antibody Deficiency And Immune Dysregulation, Plcg2-Associated

Plcg2-Associated Antibody Deficiency And Immune Dysregulation

Familial Cold Urticaria With Common Variable Immunodeficiency

Plcg2 Associated Antibody Deficiency And Immune Dysregulation

Antibody Deficiency And Immune Dysregulation Placg2-Associated

Autoinflammatory Syndrome, Cold, Familial, Type 3
Ptosis

Blepharoptosis

Drooping Eyelid

Droopy Eyelid

Ptosis Of Eyelid

Paralysis Of Levator Palpebrae Superioris
Nephronophthisis 3

NPHP3

Nph3

Adolescent Nephronophthisis

Nephronophthisis, Type 3
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16094 ZMYND11 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus ZMYND11 MGD MGI:1913755
Macaca mulatta ZMYND11 VGNC VGNC:79060
Bos taurus ZMYND11 VGNC VGNC:37202
Rattus norvegicus ZMYND11 RGD RGD:1303252
Canis familiaris ZMYND11 VGNC VGNC:48651
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