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  3. Grm3 - glutamate receptor, metabotropic 3 Gene

Grm3 - glutamate receptor, metabotropic 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：谷氨酸受体，代谢型 3

种属: Mus musculus

同用名: mGlu3; Gprc1c; mGluR3; 0710001G23Rik

基因 ID: 108069 | 基因类型: protein coding

关于 Grm3

Chromosome 5: 9,535,541-9,775,170 reverse strand.GRCm39:CM000998.3

This gene has 1 transcript (splice variant), 215 orthologues, 7 paralogues and is associated with 22 phenotypes. Biased expression in cortex adult (RPKM 11.5), frontal lobe adult (RPKM 9.3) and 4 other tissues.

功能概要

该基因编码的蛋白可启动钙通道调节剂活性和第 II 组代谢型谷氨酸受体活性。作用于基因表达的上游或内部。位于多个细胞成分中，包括谷氨酸能突触；突触后密度；和突触膜。是突触后膜的组成部分。是突触前膜的组成部分。以多种结构表达，包括消化系统；中枢神经系统;泌尿生殖系统；免疫系统;和视觉系统。与人类 GRM3（谷氨酸代谢受体 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Calcium Channel regulator activity and group II metabotropic glutamate receptor activity. Acts upstream of or within gene expression. Located in several cellular components, including glutamatergic synapse; postsynaptic density; and synaptic membrane. Is integral component of postsynaptic membrane. Is integral component of presynaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and visual system. Orthologous to human GRM3 (glutamate metabotropic receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Grm3 基因产物(1)

mRNA Protein Name
NM_181850.2 NP_862898.1 metabotropic glutamate receptor 3 precursor

Grm3 蛋白结构

PBP1_mGluR_groupII

PBP1_mGluR_groupII: cd06375 (32 - 493)

NCD3G

NCD3G: pfam07562 (504 - 554)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (574 - 599)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (574 - 827)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (611 - 632)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (641 - 665)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (687 - 707)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (732 - 758)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (766 - 789)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (796 - 821)

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  • 879 a.a.
蛋白主名 其他名称

metabotropic glutamate receptor 3

G protein-coupled receptor, family C, group 1, member C

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05825 GRM3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05826 Grm3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05827 Grm3 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grm3 NCBI NCBI:2913
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