1. Gene
  2. DBF4 - DBF4 zinc finger Gene

DBF4 - DBF4 zinc finger Gene

中文名称:DBF4 锌指

种属: Homo sapiens

同用名: ASK; CHIF; DBF4A; ZDBF1

基因 ID: 10926 | 基因类型: protein coding

关于 DBF4

Cytogenetic location: 7q21.12 Genomic coordinates (GRCh38): 7:87,876,493-87,909,553 (from NCBI)

This gene has 8 transcripts (splice variants), 210 orthologues and 1 paralogue. Biased expression in testis (RPKM 30.3), bone marrow (RPKM 10.3) and 9 other tissues.

功能概要

预测启用蛋白丝氨酸/苏氨酸激酶激活剂活性。预计参与核细胞周期 DNA 复制的正调控和细胞周期相变的调控。位于核体。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication and regulation of cell cycle phase transition. Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

DBF4 基因产物(4)

mRNA Protein Name
NM_001318060.2 NP_001304989.1 protein DBF4 homolog A isoform 2
NM_001318061.2 NP_001304990.1 protein DBF4 homolog A isoform 3
NM_001318062.2 NP_001304991.1 protein DBF4 homolog A isoform 4
NM_006716.4 NP_006707.1 protein DBF4 homolog A isoform 1

DBF4 蛋白结构

zf-DBF

zf-DBF: DBF zinc finger (290 - 334)

  • 0
  • 200
  • 400
  • 600
  • 674 a.a.
蛋白主名 其他名称

protein DBF4 homolog A

DBF4 homolog

关联疾病

疾病名称 别名
Meier-Gorlin Syndrome 1

Meier-Gorlin Syndrome

Ear, Patella, Short Stature Syndrome

Microtia, Absent Patellae, Micrognathia Syndrome

MGORS1

Eps

Ear-Patella-Short Stature Syndrome

Ear Patella Short Stature Syndrome

Microtia Absent Patellae Micrognathia Syndrome

Meier-Gorlin Syndrome, Type 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus DBF4 MGD MGI:1351328
Canis familiaris DBF4 VGNC VGNC:39780
Macaca mulatta DBF4 VGNC VGNC:71645
Rattus norvegicus DBF4 RGD RGD:1305854
Bos taurus DBF4 VGNC VGNC:27887
Felis catus DBF4 VGNC VGNC:61345