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  3. MORF4L1 - mortality factor 4 like 1 Gene

MORF4L1 - mortality factor 4 like 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：死亡率 4 等于 1

种属: Homo sapiens

同用名: Eaf3; MEAF3; MRG15; FWP006; S863-6; HsT17725; MORFRG15

基因 ID: 10933 | 基因类型: protein coding

关于 MORF4L1

Cytogenetic location: 15q25.1 Genomic coordinates (GRCh38): 15:78,872,890-78,898,139 (from NCBI)

This gene has 23 transcripts (splice variants), 280 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 192.5), brain (RPKM 119.7) and 25 other tissues.

功能概要

启用蛋白质 N 末端结合活性。通过同源重组和组蛋白修饰参与双链断裂修复。位于核斑点。 NuA4 组蛋白乙酰转移酶复合物和 Sin3 复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein N-terminus binding activity. Involved in double-strand break repair via homologous recombination and histone modification. Located in nuclear speck. Part of NuA4 Histone Acetyltransferase complex and Sin3 complex. [provided by Alliance of Genome Resources, Apr 2022]

MORF4L1 基因产物(5)

mRNA Protein Name
NM_001265603.2 NP_001252532.1 mortality factor 4-like protein 1 isoform 3
NM_001265604.2 NP_001252533.1 mortality factor 4-like protein 1 isoform 3
NM_001265605.2 NP_001252534.1 mortality factor 4-like protein 1 isoform 3
NM_006791.4 NP_006782.1 mortality factor 4-like protein 1 isoform 1
NM_206839.3 NP_996670.1 mortality factor 4-like protein 1 isoform 2

MORF4L1 蛋白结构

Tudor-knot

Tudor-knot: RNA binding activity-knot of a chromodomain (12 - 51)

MRG

MRG: MRG (176 - 350)

  • 0
  • 100
  • 200
  • 300
  • 362 a.a.
蛋白主名 其他名称

mortality factor 4-like protein 1

Esa1p-associated factor 3 homolog

关联疾病

疾病名称 别名
Paraneoplastic Cerebellar Degeneration

Pcd

Paraneoplastic Cerebellar Ataxia

Rapidely Progressive Cerebellar Syndrome

Subacute Cerebellar Degeneration
Wolf-Hirschhorn Syndrome

Pitt-Rogers-Danks Syndrome

WHS

Chromosome 4p16.3 Deletion Syndrome

Wittwer Syndrome

4p- Syndrome

Pitt Syndrome

4p Deletion Syndrome

Distal Deletion 4p

Distal Monosomy 4p

Telomeric Deletion 4p

Prds

4p Syndrome

Chromosome 4p Syndrome

Microcephaly, Iugr, Hypertelorism, Ptosis, Iris Coloboma, Hooked Nose, External Ear Dysplasia, Psychomotor Retardation

Wolf Syndrome

Chromosome 4p Deletion Syndrome

Chromosome 4p Monosomy

Del Syndrome

Monosomy 4p

Partial Monosomy 4p

Chromosome 4 Short Arm Deletion
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08593 MORF4L1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris MORF4L1 VGNC VGNC:56001
Rattus norvegicus MORF4L1 RGD RGD:1307938
Felis catus MORF4L1 VGNC VGNC:97512
Mus musculus MORF4L1 MGD MGI:1096551
Macaca mulatta MORF4L1 VGNC VGNC:84396
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