2. Gene
  3. Arrb1 - arrestin, beta 1 Gene

Arrb1 - arrestin, beta 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 1200006I17Rik; G430100A01Rik

基因 ID: 109689 | 基因类型: protein coding

关于 Arrb1

功能概要

Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process and mitogen-activated protein kinase kinase binding activity. Involved in several processes, including negative regulation of Notch signaling pathway; positive regulation of cell communication; and regulation of cellular protein metabolic process. Acts upstream of or within phototransduction and regulation of G protein-coupled receptor signaling pathway. Located in cytosol and pseudopodium. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and respiratory system. Orthologous to human ARRB1 (Arrestin beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Arrb1 基因产物(2)

mRNA Protein Name
NM_177231.2 NP_796205.1 beta-arrestin-1 isoform A
NM_178220.3 NP_835738.1 beta-arrestin-1 isoform B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process IMP
IMP: 通过突变表型推断
19915011 MGI
enables mitogen-activated protein kinase kinase binding IDA
IDA: 通过直接分析推断
19915011 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11546805 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of Notch signaling pathway IMP
IMP: 通过突变表型推断
23886940 MGI
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: 通过突变表型推断
19915011 MGI
acts upstream of or within phototransduction IMP
IMP: 通过突变表型推断
11853756 MGI
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
19915011 MGI
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
19915011 MGI
involved in positive regulation of peptidyl-serine phosphorylation IMP
IMP: 通过突变表型推断
19915011 MGI
involved in positive regulation of protein binding IMP
IMP: 通过突变表型推断
19915011 MGI
acts upstream of or within regulation of G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
9400383 MGI
involved in regulation of apoptotic process IMP
IMP: 通过突变表型推断
19915011 MGI
involved in ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
23886940 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
19915011 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
11171997 MGI
located in pseudopodium IDA
IDA: 通过直接分析推断
12821670 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

beta-arrestin-1

beta-arrestin1

Arrb1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Arrb1 Q8BWG8 Mdm2 Mus musculus P23804
Y2H
15102471
种属内
Arrb1 Q8BWG8 Hax1 Mus musculus O35387
Y2H
15102471
种属内
Arrb1 Q8BWG8 Dnajb6 Mus musculus O54946
Y2H
15102471
种属内
Arrb1 Q8BWG8 Nfe2l2 Mus musculus Q60795
Y2H
15102471
种属内
Arrb1 Q8BWG8 Card10 Mus musculus P58660
Anti Tag CoIP
18952848
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01028 ARRB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18162 Arrb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24636 Arrb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arrb1 NCBI NCBI:408
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