2. Gene
  3. Itga1 - integrin alpha 1 Gene

Itga1 - integrin alpha 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Vla1; CD49A; E130012M19Rik

基因 ID: 109700 | 基因类型: protein coding

关于 Itga1

功能概要

Predicted to enable Collagen binding activity involved in cell-matrix adhesion; protein Phosphatase binding activity; and signaling receptor binding activity. Involved in negative regulation of epidermal growth factor receptor signaling pathway. Acts upstream of or within cell adhesion; cellular extravasation; and neutrophil chemotaxis. Located in basal part of cell and external side of plasma membrane. Is expressed in blood vessel endothelium; embryo mesenchyme; intestine smooth muscle; and lung. Orthologous to human ITGA1 (Integrin subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Itga1 基因产物(1)

mRNA Protein Name
NM_001033228.3 NP_001028400.2 integrin alpha-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11470831 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell adhesion IMP
IMP: 通过突变表型推断
10528208 MGI
acts upstream of or within cellular extravasation IMP
IMP: 通过突变表型推断
10528208 MGI
involved in negative regulation of epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
15592458 MGI
acts upstream of or within neutrophil chemotaxis IMP
IMP: 通过突变表型推断
10528208 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basal part of cell IDA
IDA: 通过直接分析推断
11767049 MGI
located in cell surface IDA
IDA: 通过直接分析推断
23023225 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
9553049 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

integrin alpha-1

CD49 antigen-like family member A

VLA-1

laminin and collagen receptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06945 ITGA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19449 Itga1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25941 Itga1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991434 SAN-300 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itga1 NCBI NCBI:3672
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