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  2. RAB35 - RAB35, member RAS oncogene family Gene

RAB35 - RAB35, member RAS oncogene family Gene

中文名称:RAB35,RAS 致癌基因家族成员

种属: Homo sapiens

同用名: RAY; H-ray; RAB1C

基因 ID: 11021 | 基因类型: protein coding

关于 RAB35

Cytogenetic location: 12q24.23 Genomic coordinates (GRCh38): 12:120,095,099-120,116,753 (from NCBI)

This gene has 6 transcripts (splice variants), 220 orthologues and 68 paralogues. Ubiquitous expression in spleen (RPKM 16.4), appendix (RPKM 14.7) and 25 other tissues.


启用 GTPase 活动;胍基核糖核苷酸结合活性;和磷脂酰肌醇-4,5-二磷酸结合活性。参与多个过程,包括内体运输;质膜到核内体的运输;和蛋白质定位到核内体。位于几种细胞成分中,包括网格蛋白包被的内吞囊泡;网格蛋白涂层坑;和细胞间桥。 [由基因组资源联盟提供,2022 年 4 月]

Enables GTPase activity; guanyl ribonucleotide binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including endosomal transport; plasma membrane to endosome transport; and protein localization to endosome. Located in several cellular components, including clathrin-coated endocytic vesicle; clathrin-coated pit; and intercellular bridge. [provided by Alliance of Genome Resources, Apr 2022]

RAB35 基因产物(2)

mRNA Protein Name
NM_001167606.2 NP_001161078.1 ras-related protein Rab-35 isoform 2
NM_006861.7 NP_006852.1 ras-related protein Rab-35 isoform 1

RAB35 蛋白结构


Ras: Ras family (10 - 168)

  • 0
  • 100
  • 201 a.a.
蛋白主名 其他名称

ras-related protein Rab-35

GTP-binding protein RAY


疾病名称 别名
Familial Renal Oncocytoma
Lowe Oculocerebrorenal Syndrome

Lowe Syndrome

Oculocerebrorenal Syndrome


Oculocerebrorenal Syndrome Of Lowe


Phosphatidylinositol 4,5-Bisphosphate 5-Phosphatase Deficiency

Lowe Disease

Phosphatidylinositol 4,5-Biphosphate 5-Phosphatase Deficiency

Cerebrooculorenal Syndrome

Phosphatidylinositol-4,5-Bisphosphate-5-Phosphatase Deficiency

Lowe Oculo-Cerebro-Renal Dystrophy

Lowe Oculo-Cerebro-Renal Syndrome

Lowe Oculocerebrorenal Dystrophy


Chromosome 11p Deletion Syndrome

Oculocerebrorenal Dystrophy

Cerebro-Oculorenal Dystrophy

Ocrl1 - [Oculocerebrorenal Syndrome]

Lowe-Terrey-Maclachlan Syndrome


Deafness, Onychodystrophy, Osteodystrophy, Mental Retardation, And Seizures Syndrome

Door Syndrome

Doors Syndrome

Digitorenocerebral Syndrome

Autosomal Recessive Deafness-Onychodystrophy Syndrome

Deafness-Onychoosteodystrophy-Intellectual Disability Syndrome


Drc Syndrome

Eronen Syndrome

Deafness-Onychodystrophy-Osteodystrophy-Intellectual Disability Syndrome

Brachydactyly Due To Absence Of Distal Phalanges

Deafness-Onychodystrophy-Osteodystrophy-Intellectual Disability-Seizures Syndrome

Deafness, Onychodystrophy, Osteodystrophy, And Mental Retardation Syndrome

Deafness-Oncychodystrophy-Osteodystrophy-Intellectual Disability Syndrome

Autosomal Recessive Hearing Loss-Onychodystrophy Syndrome

Hearing Loss-Onychodystrophy-Osteodystrophy-Intellectual Disability Syndrome

Hearing Loss-Onychodystrophy-Osteodystrophy-Intellectual Disability-Seizures Syndrome

Hearing Loss-Onychoosteodystrophy-Intellectual Disability Syndrome

Deafness, Onychodystrophy, Osteodystrophy, Intellectual Disability, And Seizures Syndrome

Deafness, Congenital Onychodystrophy, Recessive Form

Deafness, Onychodystrophy, Osteodystrophy, Mental Retardation Syndrome

Legionnaire Disease

Legionnaires' Disease

Legionnaires Disease

Legionnaire Disease, Susceptibility To


Legionella Pneumonia

Infection By Legionella Pneumophilia

Legionnaire'S Disease


Legionaire Disease, Susceptibility To

Legionnaires Pneumonia


Legionella Infection

Pontiac Fever

Legionnaires' Disease

Infection By Legionella Pneumophilia

Legionella Pneumophila Infection

Warburg Micro Syndrome 1

Warburg Micro Syndrome

Micro Syndrome



Warburg Sjo Fledelius Syndrome

Warburg-Sjo-Fledelius Syndrome

Micro Syndrome 1

Microcephaly, Microcornea, Congenital Cataract, Intellectual Disability, Optic Atrophy And Hypogenitalism

Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease



Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease


Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma


种属 基因名 来源 基因 ID
Rattus norvegicus RAB35 RGD RGD:1306362
Felis catus RAB35 VGNC VGNC:107720
Canis familiaris RAB35 VGNC VGNC:45278
Bos taurus RAB35 VGNC VGNC:33644
Mus musculus RAB35 MGD MGI:1924657