2. Gene
  3. PRSS23 - serine protease 23 Gene

PRSS23 - serine protease 23 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：丝氨酸蛋白酶 23

种属: Homo sapiens

同用名: SIG13; SPUVE; ZSIG13

基因 ID: 11098 | 基因类型: protein coding

关于 PRSS23

Cytogenetic location: 11q14.2 Genomic coordinates (GRCh38): 11:86,791,071-86,952,910 (from NCBI)

This gene has 9 transcripts (splice variants), 176 orthologues and 1 paralogue. Ubiquitous expression in gall bladder (RPKM 19.0), urinary bladder (RPKM 17.9) and 24 other tissues.

功能概要

该基因编码丝氨酸蛋白酶胰蛋白酶家族的一个保守成员。小鼠研究发现诱导排卵后该基因的 mRNA 水平降低。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 6 月]

This gene encodes a conserved member of the trypsin family of serine proteases. Mouse studies found a decrease of mRNA levels of this gene after ovulation was induced. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

PRSS23 基因产物(3)

mRNA Protein Name
NM_001293179.2 NP_001280108.1 serine protease 23 precursor
NM_001293180.2 NP_001280109.1 serine protease 23 precursor
NM_007173.6 NP_009104.3 serine protease 23 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PRSS23 蛋白结构

Trypsin

Trypsin: Trypsin (148 - 289)

  • 0
  • 100
  • 200
  • 300
  • 383 a.a.
蛋白主名 其他名称

serine protease 23

protease, serine 23

PRSS23 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PRSS23 O95084 SEC11C Homo sapiens Q9BY50
Validated Y2H
32296183
种属内
PRSS23 O95084 SEC11C Homo sapiens Q9BY50
Y2H Prey Pooling
32296183
种属内
PRSS23 O95084 SEC11C Homo sapiens Q9BY50
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Exudative Vitreoretinopathy 1

Retinopathy Of Prematurity

Retrolental Fibroplasia

EVR1

Criswick-Schepens Syndrome

Rop

Exudative Vitreoretinopathy, Familial, Autosomal Dominant

Fevr, Autosomal Dominant

Premature Retinopathy

Vitreoretinopathy, Exudative 1

Autosomal Dominant Familial Exudative Vitreoretinopathy

Fevr

Vitreoretinopathy, Exudative, Type 1

Retinopathy Of Prematurity Nos

Rlf- [Retrolental Fibroplasia]

Rop - [Retinopathy Of Prematurity]

Terry Syndrome
Coats Disease

Exudative Retinopathy

Retinal Telangiectasis

Coats' Disease

Leber Miliary Aneurysm

Coats' Syndrome

Congenital Retinal Telangiectasia
Exudative Vitreoretinopathy

Familial Exudative Vitreoretinopathy

Fevr

Criswick-Schepens Syndrome

Exudative Vitreoretinopathy, Familial

Vitreoretinopathy, Exudative )

Exudative Vitreoretinopathy 1
Norrie Disease

Atrophia Bulborum Hereditaria

Episkopi Blindness

Pseudoglioma

ND

Norrie-Warburg Disease

Anderson-Warburg Syndrome

Fetal Iritis Syndrome

Norrie Syndrome

Norrie-Warburg Syndrome

Ndp

Congenital Progressive Oculo-Acoustico-Cerebral Degeneration

Norrie'S Disease

Oligophrenia Microphthalmus

Pseudoglioma Congenita

Whitnall-Norman Syndrome
Fundus Dystrophy

Retinal Dystrophy

Retinal Dystrophies

Dystrophy, Retinal
Marginal Corneal Ulcer
Vascular Skin Disease

Skin Diseases, Vascular

Skin Vascular Disease
Keipert Syndrome

Nasodigitoacoustic Syndrome

KPTS

Nasodigitoacoustic Syndrome, Formerly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11251 PRSS23 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21179 Prss23 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27696 Prss23 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus PRSS23 VGNC VGNC:64397
Macaca mulatta PRSS23 VGNC VGNC:76253
Bos taurus PRSS23 VGNC VGNC:33416
Mus musculus PRSS23 MGD MGI:1923703
Rattus norvegicus PRSS23 RGD RGD:1359545
Canis familiaris PRSS23 VGNC VGNC:45065
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