CA5B - carbonic anhydrase 5B Gene

中文名称：碳酸酐酶 5B

种属: Homo sapiens

同用名: CAVB; CA-VB

关于 CA5B

功能概要

碳酸酐酶 (CA) 是一大类锌金属酶，可催化二氧化碳的可逆水合。它们参与多种生物过程，包括呼吸、钙化、酸碱平衡、骨吸收以及房水、脑脊液、唾液和胃酸的形成。它们在组织分布和亚细胞定位方面表现出广泛的多样性。该基因编码碳酸酐酶 5B。 CA5B 和相关的 CA5A 基因的表达位于线粒体中，尽管 CA5B 的组织分布比 CA5A 更广，CA5A 仅限于肝脏、肾脏和骨骼肌。碳酸酐酶假基因 (CA5BP1) 与 CA5B 基因相邻，这两个位点产生 CA5BP1-CA5B 通读转录本。[RefSeq 提供，2019 年 1 月]

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes Carbonic Anhydrase 5B. CA5B, and the related CA5A gene, has its expression localized in the mitochondria though CA5B has a wider tissue distribution than CA5A, which is restricted to the liver, kidneys, and skeletal muscle. A Carbonic Anhydrase pseudogene (CA5BP1) is adjacent to the CA5B gene and these two loci produce CA5BP1-CA5B readthrough transcripts. [provided by RefSeq, Jan 2019]