2. Gene
  3. Asah2 - N-acylsphingosine amidohydrolase 2 Gene

Asah2 - N-acylsphingosine amidohydrolase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 114104 | 基因类型: protein coding

关于 Asah2

功能概要

Enables dihydroceramidase activity and phytoceramidase activity. Involved in response to organic substance and sphingolipid metabolic process. Located in extracellular space; mitochondrion; and plasma membrane. Is integral component of plasma membrane. Colocalizes with membrane raft. Orthologous to several human genes including ASAH2B (N-acylsphingosine amidohydrolase 2B). [provided by Alliance of Genome Resources, Apr 2022]

Asah2 基因产物(1)

mRNA Protein Name
NM_053646.2 NP_446098.1 neutral ceramidase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables N-acylsphingosine amidohydrolase activity IDA
IDA: 通过直接分析推断
10488143 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ceramide biosynthetic process IDA
IDA: 通过直接分析推断
11278489 RGD
involved in ceramide catabolic process IDA
IDA: 通过直接分析推断
10488143 RGD
involved in sphingosine biosynthetic process IDA
IDA: 通过直接分析推断
10488143 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
12499379 RGD
located in membrane raft IDA
IDA: 通过直接分析推断
11328816 RGD
NOT located in mitochondrion IDA
IDA: 通过直接分析推断
15123644 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
21613224 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
11328816 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neutral ceramidase

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

NCDase

acylsphingosine deacylase 2

neutral/alkaline ceramidase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01054 ASAH2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19409 Asah2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25901 Asah2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Asah2 NCBI NCBI:56624
Mus musculus Asah2 NCBI NCBI:54447
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