OSBPL9 - oxysterol binding protein like 9 Gene

中文名称：氧固醇结合蛋白 9

种属: Homo sapiens

同用名: ORP9; ORP-9

关于 OSBPL9

功能概要

该基因编码氧固醇结合蛋白 (OSBP) 家族的成员，该家族是一组细胞内脂质受体。大多数成员包含一个 N 端 pleckstrin 同源结构域和一个高度保守的 C 端 OSBP 样甾醇结合结构域，尽管一些成员仅包含甾醇结合结构域。该家族成员的功能是调节高尔基体结构和功能的胆固醇转移蛋白。已经确定了多个转录本变体，其中大部分编码不同的亚型。已在 3、11 和 12 号染色体上鉴定出相关的假基因。[RefSeq 提供，2010 年 7 月]

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a Cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]