2. Gene
  3. Adra1a - adrenergic receptor, alpha 1a Gene

Adra1a - adrenergic receptor, alpha 1a Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Adra1c

基因 ID: 11549 | 基因类型: protein coding

关于 Adra1a

功能概要

This gene encodes one of several multipass transmembrane proteins that function as G protein-coupled receptors. The encoded protein binds to epinephrine and norepinephrine to mediate signaling in cells of the cardiac, nervous, and Other organ systems. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]

Adra1a 基因产物(4)

mRNA Protein Name
NM_001271759.1 NP_001258688.1 alpha-1A adrenergic receptor isoform 2
NM_001271760.1 NP_001258689.1 alpha-1A adrenergic receptor isoform 1
NM_001271761.1 NP_001258690.1 alpha-1A adrenergic receptor isoform 3
NM_013461.4 NP_038489.2 alpha-1A adrenergic receptor isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables alpha1-adrenergic receptor activity IDA
IDA: 通过直接分析推断
9630362 MGI
enables alpha1-adrenergic receptor activity IMP
IMP: 通过突变表型推断
12782680 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of MAPK cascade IGI
IGI: 通过遗传相互作用推断
12782680 MGI
acts upstream of or within adult heart development IGI
IGI: 通过遗传相互作用推断
12782680 MGI
acts upstream of or within cell growth involved in cardiac muscle cell development IGI
IGI: 通过遗传相互作用推断
12782680 MGI
acts upstream of or within negative regulation of autophagy IDA
IDA: 通过直接分析推断
27994061 MGI
acts upstream of or within negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure IMP
IMP: 通过突变表型推断
12093905 MGI
involved in neuron-glial cell signaling IGI
IGI: 通过遗传相互作用推断
10493741 MGI
acts upstream of or within norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure IMP
IMP: 通过突变表型推断
12093905 MGI
acts upstream of or within organ growth IGI
IGI: 通过遗传相互作用推断
12782680 MGI
involved in pilomotor reflex IDA
IDA: 通过直接分析推断
21335239 MGI
acts upstream of or within positive regulation of MAPK cascade IGI
IGI: 通过遗传相互作用推断
12782680 MGI
acts upstream of or within positive regulation of cardiac muscle hypertrophy IDA
IDA: 通过直接分析推断
27994061 MGI
acts upstream of or within positive regulation of heart rate by epinephrine-norepinephrine IGI
IGI: 通过遗传相互作用推断
12782680 MGI
acts upstream of or within positive regulation of non-membrane spanning protein tyrosine kinase activity IDA
IDA: 通过直接分析推断
27994061 MGI
involved in positive regulation of smooth muscle contraction IDA
IDA: 通过直接分析推断
21335239 MGI
acts upstream of or within positive regulation of the force of heart contraction by epinephrine-norepinephrine IGI
IGI: 通过遗传相互作用推断
12595294 MGI
involved in regulation of blood pressure IMP
IMP: 通过突变表型推断
26531127 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
9630362 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alpha-1A adrenergic receptor

alpha-1A adrenoceptor

alpha-1A adrenoreceptor

alpha-1C adrenergic receptor

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00408 ADRA1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS00410 ADRA1D Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21088 Adra1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27606 Adra1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adra1a NCBI NCBI:148
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