Bak1 - BCL2-antagonist/killer 1 Gene

中文名称：BCL2-拮抗因子/杀手 1

种属: Rattus norvegicus

同用名: Bak

关于 Bak1

功能概要

该基因编码的蛋白可启动多项功能，包括伴侣绑定活动；热休克蛋白结合活性；和相同的蛋白质结合活性。参与多个过程，包括动物器官发育；正调节细胞色素 c 从线粒体中释放；和从线粒体中释放细胞色素 c。位于胞质溶胶中；膜;和线粒体。间歇性跛行的生物标志物。该基因的人类直系同源物与共济失调毛细血管扩张症和宫颈癌有关。与人类 BAK1（BCL2 拮抗剂/杀手 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including chaperone binding activity; heat shock protein binding activity; and identical protein binding activity. Involved in several processes, including animal organ development; positive regulation of release of cytochrome c from mitochondria; and release of cytochrome c from mitochondria. Located in cytosol; membrane; and mitochondrion. Biomarker of intermittent claudication. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Orthologous to human BAK1 (BCL2 antagonist/killer 1). [provided by Alliance of Genome Resources, Apr 2022]