2. Gene
  3. Timp1 - TIMP metallopeptidase inhibitor 1 Gene

Timp1 - TIMP metallopeptidase inhibitor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Timp; TIMP-1

基因 ID: 116510 | 基因类型: protein coding

关于 Timp1

功能概要

Enables protease binding activity. Involved in several processes, including cartilage development; response to peptide hormone; and wound healing. Located in basement membrane. Used to study degenerative disc disease. Biomarker of cholestasis; gastric ulcer; heart disease (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to human TIMP1 (TIMP metallopeptidase inhibitor 1). [provided by Alliance of Genome Resources, Apr 2022]

Timp1 基因产物(1)

mRNA Protein Name
NM_053819.1 NP_446271.1 metalloproteinase inhibitor 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protease binding IPI
IPI: 通过物理相互作用推断
21846328 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
28659595 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cartilage development IEP
IEP: 通过表达模式推断
16208432 RGD
involved in cellular response to peptide IEP
IEP: 通过表达模式推断
17555880 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
12081564 RGD
involved in response to cytokine IEP
IEP: 通过表达模式推断
10435007 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
1327205 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basement membrane IDA
IDA: 通过直接分析推断
9579471 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

metalloproteinase inhibitor 1

tissue inhibitor of metallopeptidase 1

tissue inhibitor of metalloproteinase 1

tissue inhibitor of metalloproteinases 1

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-154919 DC-Y13-27 99.52% 否
HY-47888 PLN-1474 Inhibitor 99.35% 否
HY-151932 FXR agonist 3 Agonist 95.94% 否
HY-147195 QH536 Inhibitor / 否
HY-172258 5-HT2B antagonist-2 Inhibitor / 否
HY-RS14538 TIMP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-162902 ALK5-IN-82 Inhibitor / 否
HY-RS16840 Timp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23282 Timp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Timp1 NCBI NCBI:7076
Mus musculus Timp1 NCBI NCBI:21857
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