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  2. Tbp - TATA box binding protein Gene

Tbp - TATA box binding protein Gene

种属: Rattus norvegicus

同用名: TFIID

基因 ID: 117526 | 基因类型: protein coding

关于 Tbp

功能概要

Enables DNA binding activity. Contributes to RNA polymerase II general transcription initiation factor activity. Involved in positive regulation of transcription, DNA-templated and spermatogenesis. Located in nucleus. Part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in late onset Parkinson's disease; schizophrenia; spinocerebellar ataxia type 17; and type 1 diabetes mellitus. Orthologous to human TBP (TATA-box binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Tbp 基因产物(1)

mRNA Protein Name
NM_001004198.1 NP_001004198.1 TATA-box-binding protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
16112330 RGD
contributes to RNA polymerase II general transcription initiation factor activity IDA
IDA: 通过直接分析推断
7980586 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10471789 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
7980586 RGD
involved in spermatogenesis IEP
IEP: 通过表达模式推断
8776734 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of transcription factor TFIID complex IDA
IDA: 通过直接分析推断
7980586 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

TATA-box-binding protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tbp NCBI NCBI:6908
Macaca fascicularis Tbp NCBI NCBI:101866697
Mus musculus Tbp NCBI NCBI:21374