2. Gene
  3. Tbp - TATA box binding protein Gene

Tbp - TATA box binding protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gtf2d; SCA17; TFIID; GTF2D1

基因 ID: 21374 | 基因类型: protein coding

关于 Tbp

功能概要

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Acts upstream of or within transcription by RNA polymerase II and transcription by RNA polymerase III. Located in cytoplasm; female pronucleus; and male pronucleus. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and retina. Used to study spinocerebellar ataxia type 17. Human ortholog(s) of this gene implicated in late onset Parkinson's disease; schizophrenia; spinocerebellar ataxia type 17; and type 1 diabetes mellitus. Orthologous to human TBP (TATA-box binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Tbp 基因产物(1)

mRNA Protein Name
NM_013684.3 NP_038712.3 TATA-box-binding protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
15601870 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
21245044 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
19235719 MGI
contributes to protein binding IPI
IPI: 通过物理相互作用推断
10215616 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9050847 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
12411709 MGI
acts upstream of or within transcription by RNA polymerase III IMP
IMP: 通过突变表型推断
12411709 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA polymerase transcription factor SL1 complex IPI
IPI: 通过物理相互作用推断
28893950 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
12665565 MGI
located in female germ cell nucleus IDA
IDA: 通过直接分析推断
17641088 MGI
located in female pronucleus IDA
IDA: 通过直接分析推断
17641088 MGI
located in male germ cell nucleus IDA
IDA: 通过直接分析推断
12665565 MGI
located in male pronucleus IDA
IDA: 通过直接分析推断
17641088 MGI
located in nucleus IDA
IDA: 通过直接分析推断
11861477 MGI
is active in nucleus IPI
IPI: 通过物理相互作用推断
22323595 MGI
located in pronucleus IDA
IDA: 通过直接分析推断
16822332 MGI
part of transcription factor TFIID complex IDA
IDA: 通过直接分析推断
28893950 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

TATA-box-binding protein

TATA sequence-binding protein

TATA-binding factor

TATA-binding protein

TATA-box factor

TFIID core protein

transcription initiation factor TFIID TBP subunit

相关产品

Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-16579A Etifoxine Activator 99.27% Phase 3
HY-16579 Etifoxine hydrochloride Activator 99.87% Phase 3
HY-105056 Bretazenil Agonist 99.13% Phase 3
Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-172940 TBP-134 Inducer / 否
HY-RS14266 TBP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18225 Tbp Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24702 Tbp Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tbp NCBI NCBI:6908
Macaca fascicularis Tbp NCBI NCBI:101866697
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