2. Gene
  3. BAIAP2 - Baiap2 BAR/IMD domain containing adaptor protein 2 Gene

BAIAP2 - Baiap2 BAR/IMD domain containing adaptor protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Irsp53

基因 ID: 117542 | 基因类型: protein coding

关于 BAIAP2

功能概要

Enables PDZ domain binding activity; scaffold protein binding activity; and transcription coregulator binding activity. Involved in several processes, including cellular response to L-glutamate; nervous system development; and regulation of synapse organization. Located in several cellular components, including dendrite; lamellipodium; and neuron projection branch point. Is active in several cellular components, including postsynaptic cytosol; postsynaptic density, intracellular component; and presynaptic cytosol. Colocalizes with postsynaptic density. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome; attention deficit hyperactivity disorder; and autism spectrum disorder. Orthologous to human BAIAP2 (BAR/IMD domain containing adaptor protein 2). [provided by Alliance of Genome Resources, Apr 2022]

BAIAP2 基因产物(1)

mRNA Protein Name
NM_057196.1 NP_476544.1 brain-specific angiogenesis inhibitor 1-associated protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IDA
IDA: 通过直接分析推断
14596909 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
14596909 RGD
enables scaffold protein binding IPI
IPI: 通过物理相互作用推断
12421375 RGD
enables transcription coregulator binding IPI
IPI: 通过物理相互作用推断
10332026 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to L-glutamate IEP
IEP: 通过表达模式推断
15758177 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
17855387 RGD
involved in neuron differentiation IEP
IEP: 通过表达模式推断
25586189 RGD
involved in positive regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
15673667 RGD
involved in positive regulation of excitatory postsynaptic potential IMP
IMP: 通过突变表型推断
15758177 RGD
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
25586189 RGD
involved in protein localization to synapse IMP
IMP: 通过突变表型推断
15758177 RGD
involved in regulation of modification of postsynaptic actin cytoskeleton IDA
IDA: 通过直接分析推断
15673667 RGD
involved in regulation of modification of postsynaptic actin cytoskeleton IMP
IMP: 通过突变表型推断
15673667 RGD
involved in regulation of postsynapse organization IDA
IDA: 通过直接分析推断
15673667 RGD
involved in regulation of postsynapse organization IMP
IMP: 通过突变表型推断
15673667 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendritic shaft IDA
IDA: 通过直接分析推断
24639075 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
15758177 RGD
located in dendritic spine cytoplasm IDA
IDA: 通过直接分析推断
15673667 RGD
located in excitatory synapse IDA
IDA: 通过直接分析推断
24639075 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
15673667 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
15673667 RGD
located in lamellipodium IDA
IDA: 通过直接分析推断
18480067 RGD
located in microtubule IDA
IDA: 通过直接分析推断
24639075 RGD
located in neuron projection branch point IDA
IDA: 通过直接分析推断
25586189 RGD
located in neuron projection terminus IDA
IDA: 通过直接分析推断
25586189 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15758177 RGD
located in postsynapse IDA
IDA: 通过直接分析推断
15673667 RGD
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
15673667 RGD
is active in postsynaptic density IDA
IDA: 通过直接分析推断
25293574 RGD
is active in postsynaptic density IMP
IMP: 通过突变表型推断
25293574 RGD
is active in postsynaptic density, intracellular component IDA
IDA: 通过直接分析推断
15673667 RGD
located in presynapse IDA
IDA: 通过直接分析推断
15673667 RGD
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
15673667 RGD
located in secretory granule IDA
IDA: 通过直接分析推断
17120053 RGD
located in synaptic membrane IDA
IDA: 通过直接分析推断
15673667 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

brain-specific angiogenesis inhibitor 1-associated protein 2

BAI-associated protein 2

BAI1-associated protein 2

brain-specific angiogenesis inhibitor 1-associated protein 2-like

insulin receptor substrate 53

insulin receptor substrate p53

insulin receptor substrate protein of 53 kDa

insulin receptor tyrosine

BAIAP2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Baiap2 Q6GMN2 Lin7b Rattus norvegicus Q9Z252
Pull Down
14596909
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01353 BAIAP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01354 BAIAP2L1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01355 BAIAP2L2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21826 Baiap2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28343 Baiap2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens BAIAP2 NCBI NCBI:10458
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