2. Gene
  3. Arnt - aryl hydrocarbon receptor nuclear translocator Gene

Arnt - aryl hydrocarbon receptor nuclear translocator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Drnt; Hif1b; ESTM42; bHLHe2; mKIAA4051; D3Ertd557e

基因 ID: 11863 | 基因类型: protein coding

关于 Arnt

功能概要

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; nuclear receptor activity; and protein heterodimerization activity. Involved in positive regulation of protein sumoylation. Acts upstream of or within several processes, including embryonic placenta development; positive regulation of transcription by RNA polymerase II; and response to hypoxia. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (Aryl Hydrocarbon Receptor nuclear translocator). [provided by Alliance of Genome Resources, Apr 2022]

Arnt 基因产物(7)

mRNA Protein Name
NM_001037737.2 NP_001032826.1 aryl hydrocarbon receptor nuclear translocator isoform a
NM_001409517.1 NP_001396446.1 aryl hydrocarbon receptor nuclear translocator isoform c
NM_001409518.1 NP_001396447.1 aryl hydrocarbon receptor nuclear translocator isoform d
NM_001409519.1 NP_001396448.1 aryl hydrocarbon receptor nuclear translocator isoform e
NM_001409520.1 NP_001396449.1 aryl hydrocarbon receptor nuclear translocator isoform f
NM_001409522.1 NP_001396451.1 aryl hydrocarbon receptor nuclear translocator isoform g
NM_009709.4 NP_033839.2 aryl hydrocarbon receptor nuclear translocator isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
15363889 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IGI
IGI: 通过遗传相互作用推断
9000051 MGI
contributes to nuclear receptor activity IMP
IMP: 通过突变表型推断
11043581 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
8702901 MGI
enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
24001774 MGI
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
26245371 MGI
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28602820 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell differentiation IMP
IMP: 通过突变表型推断
16287860 MGI
acts upstream of or within embryonic placenta development IMP
IMP: 通过突变表型推断
16287860 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15363889 MGI
involved in positive regulation of protein sumoylation IDA
IDA: 通过直接分析推断
19251700 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
9000051 MGI
acts upstream of or within response to hypoxia IDA
IDA: 通过直接分析推断
8702901 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11025203 MGI
located in nucleus IDA
IDA: 通过直接分析推断
11025203 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
9000051 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

aryl hydrocarbon receptor nuclear translocator

HIF-1-beta

HIF1-beta

dioxin receptor, nuclear translocator

hypoxia-inducible factor 1-beta

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120087 KG-548 Inhibitor 99.92% 否
HY-D0932 Sudan IV ≥98.0% 否
HY-RS01011 ARNT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W012248 KG-655 99.87% 否
HY-112374 NPAS3-IN-1 Inhibitor 98.29% 否
HY-P10090 Apoptin-derived peptide / 否
HY-RS01012 ARNT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08421 MIA3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-D0932S Sudan IV-d6 / 否
HY-RS18908 Arnt Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25399 Arnt Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arnt NCBI NCBI:405
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