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  2. CLK3 - CDC like kinase 3 Gene

CLK3 - CDC like kinase 3 Gene

中文名称:CDC 样激酶 3

种属: Homo sapiens

同用名: PHCLK3; PHCLK3/152

基因 ID: 1198 | 基因类型: protein coding

关于 CLK3

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:74,608,372-74,630,201 (from NCBI)

This gene has 27 transcripts (splice variants), 625 orthologues and 12 paralogues. Ubiquitous expression in bone marrow (RPKM 16.0), testis (RPKM 5.8) and 25 other tissues.

功能概要

该基因编码属于丝氨酸/苏氨酸型蛋白激酶家族的蛋白质。该蛋白是一种核双特异性激酶,可调节富含丝氨酸/精氨酸 (SR) 的剪接因子家族的核内分布。已发现该基因的两个转录本变体编码不同的亚型。相关假基因位于 1 号和 9 号染色体上。[RefSeq 提供,2008 年 7 月]

This gene encodes a protein belonging to the serine/threonine type protein kinase family. This protein is a nuclear dual-specificity kinase that regulates the intranuclear distribution of the serine/arginine-rich (SR) family of splicing factors. Two transcript variants encoding different isoforms have been found for this gene. Related pseudogenes are located on chromosomes 1 and 9. [provided by RefSeq, Jul 2008]

CLK3 基因产物(2)

mRNA Protein Name
NM_001130028.2 NP_001123500.2 dual specificity protein kinase CLK3
NM_003992.5 NP_003983.2 dual specificity protein kinase CLK3

CLK3 蛋白结构

Pkinase

Pkinase: Protein kinase domain (304 - 620)

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  • 638 a.a.
蛋白主名 其他名称

dual specificity protein kinase CLK3

重组 CLK3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75678 CLK3 Protein, Human (sf9, GST) P49761-1/NP_003983.2 (M1-R490) ≥95%

直系同源

种属 基因名 来源 基因 ID
Felis catus CLK3 VGNC VGNC:60964
Rattus norvegicus CLK3 RGD RGD:621259
Mus musculus CLK3 MGD MGI:1098670
Canis familiaris CLK3 VGNC VGNC:39348
Bos taurus CLK3 VGNC VGNC:27450
Macaca mulatta CLK3 VGNC VGNC:71260