2. Gene
  3. JAML - junction adhesion molecule like Gene

JAML - junction adhesion molecule like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：结粘附分子样

种属: Homo sapiens

同用名: AMICA; Gm638; AMICA1; CREA7-1; CREA7-4

基因 ID: 120425 | 基因类型: protein coding

关于 JAML

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:118,193,725-118,225,011 (from NCBI)

This gene has 13 transcripts (splice variants), 39 orthologues and 6 paralogues. Broad expression in appendix (RPKM 34.6), spleen (RPKM 24.5) and 14 other tissues.

功能概要

启用整合素结合活性和蛋白质同源二聚化活性。通过质膜细胞粘附分子和骨髓白细胞迁移参与异嗜性细胞间粘附。位于双细胞紧密连接处；核质；和质膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables Integrin binding activity and protein homodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and myeloid leukocyte migration. Located in bicellular tight junction; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

JAML 基因产物(4)

mRNA Protein Name
NM_001098526.2 NP_001091996.1 junctional adhesion molecule-like isoform 1 precursor
NM_001286570.2 NP_001273499.1 junctional adhesion molecule-like isoform 3
NM_001286571.2 NP_001273500.1 junctional adhesion molecule-like isoform 3
NM_153206.3 NP_694938.2 junctional adhesion molecule-like isoform 2

JAML 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (25 - 135)

V-set

V-set: Immunoglobulin V-set domain (139 - 251)

  • 0
  • 100
  • 200
  • 300
  • 394 a.a.
蛋白主名 其他名称

junctional adhesion molecule-like

adhesion molecule AMICA

重组 JAML 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75895 JAML/AMICA Protein, Human (HEK293, His) Q86YT9/NP_001091996.1 (L20-L275) ≥95%
HY-P77726 JAML/AMICA Protein, Human (256a.a, HEK293, His) Q86YT9 (L20-L275) ≥95%

关联疾病

疾病名称 别名
Malignant Histiocytic Disease

Histiocytic Disorders, Malignant
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07029 JAML Human Pre-designed siRNA Set A / 否
HY-N12840 Logmalicid B / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus JAML VGNC VGNC:82038
Rattus norvegicus JAML RGD RGD:1562572
Bos taurus JAML VGNC VGNC:30370
Mus musculus JAML MGD MGI:2685484
Canis familiaris JAML VGNC VGNC:42180
Macaca mulatta JAML VGNC VGNC:73860
Others JAML NCBI
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