2. Gene
  3. ASCL4 - achaete-scute family bHLH transcription factor 4 Gene

ASCL4 - achaete-scute family bHLH transcription factor 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：achaete-scute 家族 bHLH 转录因子 4

种属: Homo sapiens

同用名: ASH-4; HASH4; bHLHa44

基因 ID: 121549 | 基因类型: protein coding

关于 ASCL4

Cytogenetic location: 12q23.3 Genomic coordinates (GRCh38): 12:107,774,704-107,776,644 (from NCBI)

This gene has 1 transcript (splice variant), 169 orthologues and 4 paralogues.

功能概要

基本的螺旋-环-螺旋转录因子，例如 ASCL4，对于确定细胞命运和许多组织的发育和分化至关重要 (Jonsson 等人，2004 [PubMed 15475265]) 。[OMIM 提供，2008 年 3 月]

Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]).[supplied by OMIM, Mar 2008]

ASCL4 基因产物(1)

mRNA Protein Name
NM_203436.3 NP_982260.3 achaete-scute homolog 4

ASCL4 蛋白结构

HLH

HLH: Helix-loop-helix DNA-binding domain (77 - 126)

  • 0
  • 100
  • 173 a.a.
蛋白主名 其他名称

achaete-scute homolog 4

achaete-scute complex homolog 4

关联疾病

疾病名称 别名
Developmental And Epileptic Encephalopathy 33

DEE33

Epileptic Encephalopathy, Early Infantile, 33

Eiee33

Developmental And Epileptic Encephalopathy, 33

Early Infantile Epileptic Encephalopathy 33

Encephalopathy, Epileptic, Early Infantile, Type 33
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01081 ASCL4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ASCL4 VGNC VGNC:38176
Mus musculus ASCL4 MGD MGI:1914591
Macaca mulatta ASCL4 VGNC VGNC:108324
Bos taurus ASCL4 VGNC VGNC:26208
Rattus norvegicus ASCL4 RGD RGD:1307533
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