2. Gene
  3. Gdf2 - growth differentiation factor 2 Gene

Gdf2 - growth differentiation factor 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bmp9

基因 ID: 12165 | 基因类型: protein coding

关于 Gdf2

功能概要

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of Smad Family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton. [provided by RefSeq, Jul 2016]

Gdf2 基因产物(1)

mRNA Protein Name
NM_019506.4 NP_062379.3 growth/differentiation factor 2 preproprotein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20406889 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in branching involved in blood vessel morphogenesis IDA
IDA: 通过直接分析推断
20406889 MGI
acts upstream of or within osteoblast differentiation IGI
IGI: 通过遗传相互作用推断
15161906 MGI
involved in positive regulation of BMP signaling pathway IDA
IDA: 通过直接分析推断
20406889 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
20406889 MGI
involved in positive regulation of angiogenesis IDA
IDA: 通过直接分析推断
20406889 MGI
involved in positive regulation of cartilage development IDA
IDA: 通过直接分析推断
19956691 MGI
involved in positive regulation of endothelial cell differentiation IDA
IDA: 通过直接分析推断
20406889 MGI
involved in positive regulation of endothelial cell proliferation IDA
IDA: 通过直接分析推断
20406889 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
22783020 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18997172 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
18986983 MGI
NOT involved in regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
20406889 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
18997172 MGI
involved in vasculogenesis IDA
IDA: 通过直接分析推断
20406889 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

growth/differentiation factor 2

bone morphogenetic protein 9

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05353 GDF2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19136 Gdf2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25626 Gdf2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gdf2 NCBI NCBI:2658
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