1. Gene
  2. Pdia4 - protein disulfide isomerase associated 4 Gene

Pdia4 - protein disulfide isomerase associated 4 Gene

种属: Mus musculus

同用名: Cai; Erp72; ERp-72

基因 ID: 12304 | 基因类型: protein coding

关于 Pdia4

功能概要

Predicted to enable protein disulfide isomerase activity and protein-disulfide reductase activity. Predicted to be involved in chaperone-mediated protein folding; positive regulation of protein folding; and response to endoplasmic reticulum stress. Located in cell surface and endoplasmic reticulum. Part of endoplasmic reticulum chaperone complex. Is expressed in embryo; medulla oblongata basal plate; olfactory cortex ventricular layer; and telencephalon ventricular layer. Orthologous to human PDIA4 (protein disulfide isomerase family A member 4). [provided by Alliance of Genome Resources, Apr 2022]

Pdia4 基因产物(2)

mRNA Protein Name
NM_001368756.1 NP_001355685.1 protein disulfide-isomerase A4 isoform 1 precursor
NM_009787.2 NP_033917.2 protein disulfide-isomerase A4 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IPI
IPI: 通过物理相互作用推断
28576878 MGI
enables protein disulfide isomerase activity IDA
IDA: 通过直接分析推断
28576878 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blood coagulation, fibrin clot formation IMP
IMP: 通过突变表型推断
28576878 MGI
acts upstream of or within platelet aggregation IMP
IMP: 通过突变表型推断
28576878 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
19995400 MGI
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
9493907 MGI
part of endoplasmic reticulum chaperone complex IDA
IDA: 通过直接分析推断
12475965 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein disulfide-isomerase A4

ER protein 72

calcium binding protein, intestinal

endoplasmic reticulum protein 72

endoplasmic reticulum resident protein 72

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdia4 NCBI NCBI:9601