1. Gene
  2. Cast - calpastatin Gene

Cast - calpastatin Gene

种属: Mus musculus

基因 ID: 12380 | 基因类型: protein coding

关于 Cast

功能概要

This gene encodes an inhibitor of the calcium-dependent cysteine protease, calpain. This protein plays roles in multiple processes, including Apoptosis, cell cycle regulation, and membrane fusion. Multiple protein isoforms exist which contain unique N-terminal domains, and multiple inhibitory domains that share homology with each Other. Some isoforms may be tissue-specific. Two different pseudogenes of this gene are found on chromosome 19. [provided by RefSeq, Jul 2014]

Cast 基因产物(8)

mRNA Protein Name
NM_001301153.1 NP_001288082.1 calpastatin isoform 1
NM_001301155.1 NP_001288084.1 calpastatin isoform 3
NM_001301156.1 NP_001288085.1 calpastatin isoform 4
NM_001301157.1 NP_001288086.1 calpastatin isoform 5
NM_001301158.1 NP_001288087.1 calpastatin isoform 6
NM_001301160.1 NP_001288089.1 calpastatin isoform 7
NM_001301181.1 NP_001288110.1 calpastatin isoform 8
NM_009817.4 NP_033947.1 calpastatin isoform 2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of peptidase activity IGI
IGI: 通过遗传相互作用推断
21849499 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
11090425 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

calpastatin

calpain inhibitor

calpastatin type III

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cast NCBI NCBI:831