2. Gene
  3. Scarb2 - scavenger receptor class B, member 2 Gene

Scarb2 - scavenger receptor class B, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: LGP85; Cd36l2; LIMP-2; MLGP85; LIMP II; 9330185J12Rik

基因 ID: 12492 | 基因类型: protein coding

关于 Scarb2

功能概要

This gene encodes a CD36-like type III Transmembrane Glycoprotein that localizes to the lysosomal membrane. Mice lacking the encoded protein exhibit an increased postnatal mortality caused by an obstruction of the ureteropelvic junction, deafness, peripheral demyelinating neuropathy and tubular proteinuria. [provided by RefSeq, Aug 2015]

Scarb2 基因产物(1)

mRNA Protein Name
NM_007644.4 NP_031670.1 lysosome membrane protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cargo receptor activity IMP
IMP: 通过突变表型推断
18022370 MGI
enables cholesterol binding IDA
IDA: 通过直接分析推断
29199275 MGI
enables enzyme binding IPI
IPI: 通过物理相互作用推断
18022370 MGI
enables phosphatidylcholine binding IDA
IDA: 通过直接分析推断
29199275 MGI
enables phosphatidylserine binding IDA
IDA: 通过直接分析推断
29199275 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
27789271 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
29199275 MGI
enables protein-folding chaperone binding IPI
IPI: 通过物理相互作用推断
27789271 MGI
enables scavenger receptor activity IDA
IDA: 通过直接分析推断
29199275 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in aminophospholipid transport IDA
IDA: 通过直接分析推断
29199275 MGI
acts upstream of or within endosome to plasma membrane protein transport IMP
IMP: 通过突变表型推断
16901941 MGI
involved in protein targeting to lysosome IMP
IMP: 通过突变表型推断
18022370 MGI
involved in receptor-mediated endocytosis IDA
IDA: 通过直接分析推断
29199275 MGI
involved in regulation of carbohydrate catabolic process IMP
IMP: 通过突变表型推断
18022370 MGI
involved in regulation of glucosylceramidase activity IMP
IMP: 通过突变表型推断
25316793 MGI
acts upstream of or within sensory perception of sound IMP
IMP: 通过突变表型推断
16901941 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endocytic vesicle membrane IDA
IDA: 通过直接分析推断
29199275 MGI
located in lysosomal lumen IDA
IDA: 通过直接分析推断
18022370 MGI
located in lysosomal membrane IDA
IDA: 通过直接分析推断
18022370 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
29199275 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lysosome membrane protein 2

85 kDa lysosomal membrane sialoglycoprotein

CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2

lysosome membrane protein II

重组 Scarb2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72515 LIMPII/SR-B2 Protein, Mouse (406a.a, HEK293, His) O35114 (R27-T432) ≥95%
HY-P72895 CD36 Protein, Mouse (HEK293, His) Q08857 (G30-K439) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12489 SCARB2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18568 Scarb2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25052 Scarb2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Scarb2 NCBI NCBI:950
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