1. Gene
  2. Cdh6 - cadherin 6 Gene

Cdh6 - cadherin 6 Gene

种属: Mus musculus

同用名: cad6

基因 ID: 12563 | 基因类型: protein coding

关于 Cdh6

功能概要

This gene encodes a member of the Cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Mice lacking the encoded protein exhibit delay in mesenchyme-to-epithelial conversion and a loss of nephrons. Multiple distinct genes of the Cadherin family, including this gene, are found on chromosome 15. [provided by RefSeq, Oct 2015]

Cdh6 基因产物(1)

mRNA Protein Name
NM_007666.4 NP_031692.2 cadherin-6 preproprotein
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Notch signaling pathway IDA
IDA: 通过直接分析推断
23117660 MGI
involved in synaptic membrane adhesion IDA
IDA: 通过直接分析推断
28957665 MGI
involved in synaptic membrane adhesion IMP
IMP: 通过突变表型推断
28957665 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
28957665 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
28957665 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
12139922 MGI
is active in synapse IDA
IDA: 通过直接分析推断
28957665 MGI
is active in synapse IMP
IMP: 通过突变表型推断
28957665 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cadherin-6

K-cadherin

kidney cadherin

重组 Cdh6 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77037 Cadherin-6/KCAD Protein, Mouse (HEK293, His) P97326 (T19-A615) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdh6 NCBI NCBI:1004
Macaca fascicularis Cdh6 NCBI
Rattus norvegicus Cdh6 NCBI NCBI:25409