Crhr2 - corticotropin releasing hormone receptor 2 Gene

中文名称：促肾上腺皮质激素释放激素受体 2

种属: Mus musculus

同用名: Crfr2; CRF-R2; CRFR2beta; CRFR2alpha

关于 Crhr2

功能概要

该基因编码的蛋白可启动促肾上腺皮质激素释放因子受体活性和激素活性。作用于 G 蛋白偶联受体信号通路的上游或内部；血管生成的负调节；腺苷酸环化酶激活 G 蛋白偶联受体信号通路的调控。位于高尔基体；细胞表面；和内质网。以多种结构表达，包括大脑；泌尿生殖系统；直觉;淋巴系统腺体；和外皮系统。该基因的人类直系同源物与哮喘有关。与人类 CRHR2（促肾上腺皮质激素释放激素受体 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables corticotrophin-releasing factor receptor activity and hormone activity. Acts upstream of or within G protein-coupled receptor signaling pathway; negative regulation of angiogenesis; and regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway. Located in Golgi apparatus; cell surface; and endoplasmic reticulum. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and integumental system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CRHR2 (corticotropin releasing hormone receptor 2). [provided by Alliance of Genome Resources, Apr 2022]