2. Gene
  3. Cxadr - coxsackie virus and adenovirus receptor Gene

Cxadr - coxsackie virus and adenovirus receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: CAR; MCAR; MCVADR; 2610206D03Rik

基因 ID: 13052 | 基因类型: protein coding

关于 Cxadr

功能概要

This gene encodes a protein that is part of the Cortical Thymocyte marker in Xenopus (CTX) subfamily within the immunoglobulin superfamily. Members of this subfamily, predominantly expressed on the surface of endothelial and epithelial cells, help establish cell polarity and provide a barrier function, regulating migration of immune cells. This protein, first identified as the receptor for adenovirus subgroup C and coxsakieviruses group B, is developmentally regulated and plays an important role in cardiac development. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]

Cxadr 基因产物(3)

mRNA Protein Name
NM_001025192.3 NP_001020363.1 coxsackievirus and adenovirus receptor homolog isoform a precursor
NM_001276263.1 NP_001263192.1 coxsackievirus and adenovirus receptor homolog isoform c precursor
NM_009988.4 NP_034118.1 coxsackievirus and adenovirus receptor homolog isoform b precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-catenin binding IPI
IPI: 通过物理相互作用推断
18636119 MGI
enables connexin binding IPI
IPI: 通过物理相互作用推断
18636119 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15979067 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in AV node cell to bundle of His cell communication IMP
IMP: 通过突变表型推断
18636119 MGI
involved in AV node cell-bundle of His cell adhesion involved in cell communication IMP
IMP: 通过突变表型推断
18636119 MGI
acts upstream of or within cardiac muscle cell development IMP
IMP: 通过突变表型推断
16079292 MGI
acts upstream of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
16543498 MGI
involved in cell-cell adhesion IMP
IMP: 通过突变表型推断
10814828 MGI
acts upstream of or within cell-cell junction organization IMP
IMP: 通过突变表型推断
16543498 MGI
involved in gamma-delta T cell activation IDA
IDA: 通过直接分析推断
20813954 MGI
involved in germ cell migration IEP
IEP: 通过表达模式推断
17690169 MGI
acts upstream of or within heart development IMP
IMP: 通过突变表型推断
15864812 MGI
acts upstream of or within mitochondrion organization IMP
IMP: 通过突变表型推断
16079292 MGI
acts upstream of or within negative regulation of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
16543498 MGI
involved in regulation of AV node cell action potential IMP
IMP: 通过突变表型推断
18636119 MGI
involved in regulation of synaptic vesicle endocytosis IDA
IDA: 通过直接分析推断
31043663 MGI
involved in regulation of synaptic vesicle endocytosis IMP
IMP: 通过突变表型推断
31043663 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
27629708 MGI
is active in GABA-ergic synapse IEP
IEP: 通过表达模式推断
27629708 MGI
located in acrosomal vesicle IDA
IDA: 通过直接分析推断
16410001 MGI
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
11316797 MGI
located in bicellular tight junction IDA
IDA: 通过直接分析推断
17690169 MGI
located in cell body IDA
IDA: 通过直接分析推断
10814828 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
16678988 MGI
located in filopodium IDA
IDA: 通过直接分析推断
10814828 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
27629708 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
27629708 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
31043663 MGI
located in growth cone IDA
IDA: 通过直接分析推断
10814828 MGI
located in intercalated disc IDA
IDA: 通过直接分析推断
18636119 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
10814828 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
27629708 MGI
is active in presynaptic membrane IEP
IEP: 通过表达模式推断
27629708 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

coxsackievirus and adenovirus receptor homolog

重组 Cxadr 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70052 CXADR Protein, Mouse (HEK293, Fc) P97792 (L20-G237) ≥95%
HY-P72364 CXADR Protein, Mouse (Biotinylated, HEK293, Avi-His) P97792 (L20-G237) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16275 Cxadr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03382 CXADR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23594 Cxadr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cxadr NCBI NCBI:1525
Rattus norvegicus Cxadr NCBI NCBI:89843
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