2. Gene
  3. Cyp11a1 - cytochrome P450, family 11, subfamily a, polypeptide 1 Gene

Cyp11a1 - cytochrome P450, family 11, subfamily a, polypeptide 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Scc; cscc; Cyp11a; Cypxia1; P450scc; D9Ertd411e

基因 ID: 13070 | 基因类型: protein coding

关于 Cyp11a1

功能概要

Enables Cholesterol monooxygenase (side-chain-cleaving) activity. Acts upstream of or within C21-steroid hormone biosynthetic process. Located in mitochondrion. Is expressed in several structures, including endocrine gland; labyrinthine zone; reproductive system; spleen; and urinary system. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia and congenital adrenal insufficiency. Orthologous to human CYP11A1 (Cytochrome P450 family 11 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp11a1 基因产物(2)

mRNA Protein Name
NM_001346787.1 NP_001333716.1 cholesterol side-chain cleavage enzyme, mitochondrial isoform 2
NM_019779.4 NP_062753.3 cholesterol side-chain cleavage enzyme, mitochondrial isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cholesterol monooxygenase (side-chain-cleaving) activity IDA
IDA: 通过直接分析推断
7527351 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within C21-steroid hormone biosynthetic process IDA
IDA: 通过直接分析推断
7527351 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
8111631 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cholesterol side-chain cleavage enzyme, mitochondrial

cholesterol desmolase

cytochrome P450 11A1

cytochrome P450 side-chain cleavage enzyme

cytochrome P450(scc)

cytochrome P450, 11a, cholesterol side-chain cleavage

相关产品

Approval
生物活性分子 (2)
目录号 产品名 作用方式
纯度 是否罕见病
HY-16276 Osilodrostat Inhibitor 99.90% 是
HY-16276A Osilodrostat phosphate Inhibitor 98.83% 是
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-156628 Opevesostat Inhibitor 99.79% Phase 3
Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-130705A Tachysterol 3 99.68% 否
HY-156530 CYP11A1-IN-1 Inhibitor 99.64% 否
HY-101217 BI 689648 Inhibitor 99.20% 否
HY-135281 CYP11B2-IN-1 Inhibitor 99.83% 否
HY-151140 CYP11B1-IN-2 Inhibitor / 否
HY-176480 CYP11B2-IN-3 Inhibitor / 否
HY-RS03434 CYP11A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03435 CYP11B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-163751 STING-IN-9 Inhibitor / 否
HY-RS17315 Cyp11b1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17479 Cyp11a1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23770 Cyp11b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23937 Cyp11a1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp11a1 NCBI NCBI:1583
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