2. Gene
  3. PPM1M - protein phosphatase, Mg2+/Mn2+ dependent 1M Gene

PPM1M - protein phosphatase, Mg2+/Mn2+ dependent 1M Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蛋白磷酸酶，Mg2+/Mn2+ 依赖性 1M

种属: Homo sapiens

同用名: PP2CE; PP2Ceta; PP2C-eta

基因 ID: 132160 | 基因类型: protein coding

关于 PPM1M

Cytogenetic location: 3p21.2 Genomic coordinates (GRCh38): 3:52,245,759-52,250,599 (from NCBI)

This gene has 9 transcripts (splice variants), 501 orthologues and 16 paralogues. Ubiquitous expression in lymph node (RPKM 16.5), spleen (RPKM 14.7) and 25 other tissues.

功能概要

预测可启用锰离子结合活性和磷蛋白磷酸酶活性。预测参与蛋白质去磷酸化。预测位于核内。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable manganese ion binding activity and phosphoprotein Phosphatase activity. Predicted to be involved in protein dephosphorylation. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

PPM1M 基因产物(2)

mRNA Protein Name
NM_001122870.3 NP_001116342.1 protein phosphatase 1M isoform b
NM_144641.4 NP_653242.3 protein phosphatase 1M isoform a

PPM1M 蛋白结构

PP2C

PP2C: Protein phosphatase 2C (24 - 104)

PP2C

PP2C: Protein phosphatase 2C (147 - 246)

  • 0
  • 100
  • 200
  • 270 a.a.
蛋白主名 其他名称

protein phosphatase 1M

protein phosphatase 1M (PP2C domain containing)

关联疾病

疾病名称 别名
Keratitis, Hereditary

Keratitis

Autosomal Dominant Keratitis

Hereditary Keratitis

Dominantly Inherited Keratitis

Keratitis Hereditary

KERH
Acrodysostosis

Acrodysplasia

Arkless-Graham Syndrome

Maroteaux-Malamut Syndrome

Nasal Hypoplasia-Peripheral Dysostosis-Intellectual Disability Syndrome

Peripheral Dysostosis-Nasal Hypoplasia-Intellectual Disability Syndrome
Ichthyosis

Ichthyoses

Non-Syndromic Ichthyosis

Congenital Ichthyosis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10970 PPM1M Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus PPM1M MGD MGI:1915155
Canis familiaris PPM1M VGNC VGNC:44872
Macaca mulatta PPM1M VGNC VGNC:84145
Felis catus PPM1M VGNC VGNC:64315
Bos taurus PPM1M VGNC VGNC:33217
Rattus norvegicus PPM1M RGD RGD:1584266
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