COX7A1 - cytochrome c oxidase subunit 7A1 Gene

中文名称：细胞色素 c 氧化酶亚基 7A1

种属: Homo sapiens

同用名: COX7A; COX7AH; COX7AM

关于 COX7A1

功能概要

细胞色素 c 氧化酶 (COX) 是线粒体呼吸链的末端组分，它催化电子从还原的细胞色素 c 转移到氧气。该组分是由线粒体基因编码的 3 个催化亚基和核基因编码的多个结构亚基组成的异聚复合物。线粒体编码的亚基在电子传递中起作用，而核编码的亚基可能在复合物的调节和组装中起作用。该核基因编码 VIIa 亚基的多肽 1 (肌肉亚型) ，多肽 1 仅存在于肌肉组织中。 VIIa 亚基的其他多肽存在于肌肉和非肌肉组织中，由不同的基因编码。[RefSeq 提供，2008 年 7 月]

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes. [provided by RefSeq, Jul 2008]