1. Gene
  2. Elk1 - ELK1, member of ETS oncogene family Gene

Elk1 - ELK1, member of ETS oncogene family Gene

种属: Mus musculus

同用名: Elk-1

基因 ID: 13712 | 基因类型: protein coding

关于 Elk1

功能概要

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-Fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene may produce multiple isoforms by the use of alternative translational start codons. [provided by RefSeq, Mar 2012]

Elk1 基因产物(1)

mRNA Protein Name
NM_007922.5 NP_031948.4 ETS domain-containing protein Elk-1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
12473665 MGI
enables mediator complex binding IPI
IPI: 通过物理相互作用推断
7738173 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
16549787 MGI
enables transcription regulator activator activity IMP
IMP: 通过突变表型推断
7738173 MGI
enables transcription regulator inhibitor activity IMP
IMP: 通过突变表型推断
7738173 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
31877385 MGI
acts upstream of or within liver development IMP
IMP: 通过突变表型推断
31877385 MGI
acts upstream of or within lung development IMP
IMP: 通过突变表型推断
31877385 MGI
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15896720 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12473665 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ETS domain-containing protein Elk-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Elk1 NCBI NCBI:2002