1. Gene
  2. Mark2 - MAP/microtubule affinity regulating kinase 2 Gene

Mark2 - MAP/microtubule affinity regulating kinase 2 Gene

种属: Mus musculus

同用名: Emk; EMK-1; Par-1; Par-1b

基因 ID: 13728 | 基因类型: protein coding

关于 Mark2

功能概要

Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and protein kinase activity. Predicted to be involved in several processes, including generation of neurons; protein phosphorylation; and regulation of neuron projection development. Predicted to act upstream of or within Wnt signaling pathway; cell differentiation; and phosphorylation. Located in basal cortex and nucleus. Is expressed in brain; early conceptus; and oocyte. Orthologous to human MARK2 (microtubule affinity regulating kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Mark2 基因产物(7)

mRNA Protein Name
NM_001080388.3 NP_001073857.1 serine/threonine-protein kinase MARK2 isoform 2
NM_001080389.3 NP_001073858.1 serine/threonine-protein kinase MARK2 isoform 3
NM_001080390.3 NP_001073859.1 serine/threonine-protein kinase MARK2 isoform 4
NM_001410248.1 NP_001397177.1 serine/threonine-protein kinase MARK2 isoform 5
NM_001410249.1 NP_001397178.1 serine/threonine-protein kinase MARK2 isoform 6
NM_001410250.1 NP_001397179.1 serine/threonine-protein kinase MARK2 isoform 7
NM_007928.4 NP_031954.2 serine/threonine-protein kinase MARK2 isoform 1
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basal cortex IDA
IDA: 通过直接分析推断
15950600 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
21865452 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15950600 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
21865452 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein kinase MARK2

ELKL motif kinase 1

PAR1 homolog b

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mark2 NCBI NCBI:2011